PF-06471553 NEW
| Price | $1450 | $1890 | $2800 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2026-04-20 |
Product Details
| Product Name: PF-06471553 | CAS No.: 1808094-07-6 |
| Supply Ability: 10g | Release date: 2026/04/20 |
Product Introduction
Bioactivity
| Name | PF-06471553 |
| Description | PF-06471553 is an effective and selective inhibitor of monoacylglycerol acyltransferase 3 (IC50: 92 nM). |
| In vitro | PF-06471553 shows inhibitory activity against MGAT3 in HEK-293 cells with an IC50 of 205 nM (pIC50, 6.69). PF-06471553 displays >160 fold in vitro selectivity for MGAT3 over DGAT1 (IC50, >50 μM), DGAT2 (IC50, >100 μM), MGAT1 (IC50, 14.9 μM), and MGAT2 (IC50, 19.8 μM) [1]. |
| In vivo | In hMGAT3 mice, PF-06471553 (200 mg/kg, p.o.) in addition to (DGAT1 and DGAT2) inhibitors display additional inhibition of glycerol-d5 incorporated triolein. It has no effect on WT mice[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 150 mg/mL (320.83 mM), Sonication is recommended. |
| Keywords | PF-06471553 | PF06471553 | PF 06471553 | MGAT3 |
| Inhibitors Related | Xanthohumol | Lecimibide | OSMI-3 | 2,2'-Methylenebis(6-tert-butyl-4-methylphenol) | Cyclandelate | Eldacimibe | YM17E | 2-Furoic acid | RU-SKI 43 | Eflucimibe | PF-04620110 | DGAT-1 inhibitor 2 |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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