Prodipine hydrochloride NEW
| Price | $794 | $1190 |
| Package | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-10-28 |
Product Details
| Product Name: Prodipine hydrochloride | CAS No.: 31314-39-3 |
| Supply Ability: 10g | Release date: 2025/10/28 |
Product Introduction
Bioactivity
| Name | Prodipine hydrochloride |
| Description | Prodipine hydrochloride for purified and plasma Dipeptidyl peptidase IV (DPP IV) from the rabbit (IC50 of 4.5 μM and 30 μM, respectively). |
| In vivo | in vivo applicability of Prodipine.?Male rabbits weighing 3-4 kg received a single intravenous injection with 10 mg Prodipine or saline.?After 1 hr, plasma DPP IV activity had decreased to less than 20% of the preinjection value and remained unchanged during a 24-hr observation period.?In a next step, we aimed to study (i) the dose dependency and (ii) the duration of the effect after a single intravenous dose of Prodipine.?A profound and long-lasting inhibition of plasma DPP IV activity was observed in the treated animals (1, 5 or 10 mg).?It took 5 to 8 days to reach half of the pretreatment DPP IV activity and generally more than 20 days for a complete recovery.?Systemic treatment with Prodipine not only led to inhibition of plasma DPP IV activity but also decreased tissue DPP IV activity in circulating mononuclear cells, kidney cortex, thymus, spleen, lung, and liver.?No differences in activities of the related peptidases aminopeptidase P (APP, EC 3.4.11.9), prolyl oligopeptidase (PO, EC 3.4.21.26), or aminopeptidase M (mAAP, EC 3.4.11.2) were detected between Prodipine-treated and control rabbits. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | Prodipine hydrochloride | Prodipine Hydrochloride |
| Inhibitors Related | MG-132 | Tripterin | Sitagliptin | Teneligliptin hydrobromide | Carfilzomib | Sitagliptin phosphate monohydrate | Anagliptin | Linagliptin | Vildagliptin | Alloxan monohydrate | 4'-Hydroxychalcone | Bortezomib |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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