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Postion:Product Catalog >(Rac)-Rotigotine hydrochloride
(Rac)-Rotigotine hydrochloride
  • (Rac)-Rotigotine hydrochloride

(Rac)-Rotigotine hydrochloride NEW

Price $52
Package 1mL
Min. Order:
Supply Ability: 10g
Update Time: 2025-10-27

Product Details

Product Name: (Rac)-Rotigotine hydrochloride CAS No.: 102120-99-0
Supply Ability: 10g Release date: 2025/10/27

Product Introduction

Bioactivity

Name(Rac)-Rotigotine hydrochloride
Description(Rac)-Rotigotine hydrochloride is a racemate of Rotigotine, a full agonist of the dopamine receptor and a partial agonist of the 5-HT1A receptor.
In vitroIn functional studies, Rotigotine behaves as full agonist at all dopamine receptors but notably the potency for stimulation of D1 receptors is similar to that for D2 and D3 receptors (pEC50?respectively: 9.0, 9.4-8.6, 9.7)[1]. Rotigotine (10 μM) decreases the number of THir neurons by 40% in primary mesencephalic cell culture. Rotigotine (0.01 μM) slightly protects dopaminergic neurons against MPP+?toxicity, significantly protects dopaminergic neurons against rotenone-induced cell death, and significantly inhibits ROS production by rotenone[4]. .
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 50 mg/mL (142.07 mM), Sonication is recommended.
KeywordsRotigotine Hydrochloride | DopamineReceptor | Dopamine receptor | Dopamine Receptor | (Rac)Rotigotine hydrochloride | (Rac) Rotigotine hydrochloride
Inhibitors RelatedAlverine citrate | Dapoxetine hydrochloride | Cefaclor monohydrate | Clozapine N-Oxide | Octopamine hydrochloride | 1,8-Cineole | Dexmedetomidine hydrochloride | Isoprenaline hydrochloride | Citicoline | Oxolinic acid | Trazodone hydrochloride | Mianserin hydrochloride

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

4YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, USA
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