Product Details
| Product Name:
Ro15-4513 |
CAS No.:
91917-65-6 |
| Supply Ability:
10g |
Release date:
2025/07/22 |
Product Introduction
Bioactivity
| Name | Ro15-4513 |
| Description | Ro15-4513 is imidazobenzodiazepinone derivative and is a partial inverse agonist of benzodiazepine receptors. Ro15-4513 is an effective ethanol antagonist. |
| In vitro | Ro15-4513 typically functions as a partial inverse agonist at GABAA receptors [3]. |
| In vivo | Ro 15-4513 (i.p.; 3 mg/kg; 15 min before administration of 1.5 g/kg ethanol) reverses ethanol-induced sedation in GABAA receptor δ subunit-deficient mice. Ro 15-4513 (i.p.; 3 mg/kg; 10 min before being tested) fully inhibits the ethanol-induced (1.8 g/kg) reduction in total locomotor activity and partly the reduction in rearing [2]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | Ro15-4513 | Ro-15-4513 | Ro154513 | Ro15 4513 | BZR |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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