RU-SKI 43 Hydrochloride NEW
| Price | $73 |
| Package | 2mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-11-04 |
Product Details
| Product Name: RU-SKI 43 Hydrochloride | CAS No.: 1782573-67-4 |
| Supply Ability: 10g | Release date: 2025/11/04 |
Product Introduction
Bioactivity
| Name | RU-SKI 43 Hydrochloride |
| Description | RU-SKI 43 Hydrochloride is a potent and selective inhibitor of Hedgehog acyltransferase (Hhat), with an IC50 value of 850 nM. RU-SKI 43 Hydrochloride has been reported to possess anticancer activity, making it a useful compound for investigating Hedgehog signaling in tumor biology. |
| In vitro | Method: AsPC-1 cells were treated with RU-SKI 43 Hydrochloride (10 μM, 72 hours), and Gli-1 mRNA levels were detected by qRT-PCR. Result: RU-SKI 43 Hydrochloride reduced Gli-1 levels in AsPC-1 cells by 40%. [2] |
| In vivo | After IV administration,RU-SKI 43 Hydrochloride has a t1/2 of 17 min in mouse plasma.[1] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : ≥ 40 mg/mL, Sonication is recommended. H2O : 2 mg/mL (4.73 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (4.73 mM), Sonication is recommended. |
| Keywords | RU-SKI 43 Hydrochloride | RUSKI 43 hydrochloride | RU SKI 43 hydrochloride | Hhat |
| Inhibitors Related | Itraconazole | Xanthohumol | Naftifine hydrochloride | GANT 61 | Ellagic acid | Vismodegib | Cyclandelate | Eldacimibe | YM17E | 2-Furoic acid | Tolnaftate | Sonidegib |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
You may like
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $45.00/1mg |
VIP6Y
|
TargetMol Chemicals Inc.
|
2025-07-09 | |
| $0.00/1kg |
VIP2Y
|
Shandong Hanjiang Chemical Co., Ltd
|
2024-01-22 | |
| $73.00/2mg |
VIP4Y
|
TargetMol Chemicals Inc.
|
2025-08-21 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
INQUIRY