Ruthenium Red NEW
| Price | $34 |
| Package | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-10-13 |
Product Details
| Product Name: Ruthenium Red | CAS No.: 11103-72-3 |
| Purity: 95.00% | Supply Ability: 10g |
| Release date: 2025/10/13 |
Product Introduction
Bioactivity
| Name | Ruthenium Red |
| Description | Ruthenium Red (Ammoniated ruthenium oxychloride) is a polycationic dye widely used for electron microscopy (EM) of cells, tissues and vegetative bacteria. Ruthenium red strongly reacts with phospholipids and fatty acids and binds to acidic mucopolysaccharides. Ruthenium red is a L-type calcium current (ICa) blocker, blocks Ca2+ uptake and release, and voltage-sensitive Ca2+ channels |
| Cell Research | 1. Solution preparation 1. Mother solution preparation: Dissolve Ruthenium Red in an appropriate solvent, DMSO or H2O, usually at a concentration of 1-10 mM. 2. Working solution preparation: Dilute Ruthenium Red into the required working solution using PBS/DMEM/H2O, usually at a concentration range of 1-10μM, which needs to be adjusted according to the experimental situation. 1. As a calcium current blocker 1. Cell treatment: Add Ruthenium Red working solution to the cell culture medium and incubate at different time points to observe the inhibitory effect of L-type calcium channels. 2. Calcium ion monitoring: Use calcium indicators (such as Fura-2, Fluo-4, etc.) combined with fluorescence microscopy or flow cytometry to monitor changes in intracellular calcium ion concentration. 2. For electron microscopy observation 1. Sample staining: Add Ruthenium Red working solution to cells or tissue samples, stain for a certain period of time, remove and wash with PBS. 2. Microscopic observation: Observe the sample using an electron microscope or fluorescence microscope to check the staining effect. III. Cell membrane and tissue staining: 1. Solution preparation: Dilute the Ruthenium Red stock solution in PBS or other suitable buffer, and the concentration can be adjusted to 10-50 μM. 2. Cell or tissue staining: Add the dye solution to the cell culture medium, incubate for 15-30 minutes, and then observe the labeled cell structure by fluorescence microscopy. |
| Storage | keep away from direct sunlight,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | H2O : 20 mg/mL (25.43 mM), Sonication is recommended. DMSO : 20 mg/mL (25.43 mM), Sonication is recommended. |
| Keywords | tool | sodium | Ruthenium Red | polycationic | microscopy | Inhibitor | inhibit | histology | electron | dye | current | CalciumChannel | Calcium Channel | calcium | Ca2+ channels | Ca channels |
| Inhibitors Related | Nisoldipine | Diltiazem hydrochloride | Cromolyn sodium | L-Ascorbic acid | L-Phenylalanine | D-Menthol | Ethyl cinnamate | L-Ascorbic acid sodium salt | 1-Octanol | 2-Nitrobenzoic acid | Methyl homoveratrate | Otilonium bromide |
| Related Compound Libraries | Ion Channel Targeted Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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