Sitravatinib malate NEW

Price	$1520	$1980	$2500
Package	25mg	50mg	100mg

Min. Order:
Supply Ability:	10g
Update Time:	2025-10-28

Product Details

Product Name: Sitravatinib malate	CAS No.: 2244864-88-6
Supply Ability: 10g	Release date: 2025/10/28

Product Introduction

Bioactivity

Name	Sitravatinib malate
Description	Sitravatinib malate is an orally bioavailable receptor inhibitor of tyrosine kinase (RTK) (IC50s of 1.5 nM, 2 nM, 2 nM, 5 nM, 6 nM, 6 nM, 8 nM, 0.5 nM, 29 nM, 5 nM, and 9 nM for Axl, MER, VEGFR3, VEGFR2, VEGFR1, KIT, FLT3, DDR2, DDR1, TRKA, TRKB, respectively.) , shows potent single-agent antitumor efficacy and enhances the activity of PD-1 blockade through promoting an antitumor immune microenvironment.
In vitro	In KLN205 and E0771 cell lines,Sitravatinib (0.01 nM-10 μM; 14 days) reduces colony formation in a dose-dependent manner [2]. Sitravatinib (0.001-10 μM; 5 days) inhibits tumor cell viability(IC50s : 1 μM, in KLN205), E0771 and CT1B-A5 cell lines[2].
In vivo	In C57BL/6 mice bearing CT1B-A5 cells model,Sitravatinib (20 mg/kg; p.o.; once per day for 6 days) significantly inhibits tumor progression and induces tumor regression [2].
Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Keywords	VEGFR3 \| VEGFR2 \| VEGFR1 \| TrkB \| TrkA \| TAMReceptor \| TAM Receptor \| Sitravatinib Malate \| Sitravatinib malate \| MGCD-516 Malate \| MGCD516 Malate \| MGCD 516 Malate \| MG-516 Malate \| MG516 Malate \| MG 516 Malate \| MER \| KIT \| FLT3 \| DDR2 \| DDR1 \| Axl
Inhibitors Related	Bemcentinib \| Gilteritinib \| Sunitinib \| Sorafenib \| Dasatinib \| glycine \| Regorafenib \| 7,8-Dihydroxyflavone \| Ethyl cinnamate \| Chloramphenicol \| Pazopanib \| Albendazole

Company Profile Introduction

TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds. 170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.

Recommended supplier

Product name	Price		Suppliers	Update time
Sitravatinib	$47.00/5mg	VIP6Y	TargetMol Chemicals Inc.	2025-11-10
Sunitinib Malate	$0.00/10mg	VIP8Y	Guangzhou PI PI BIOTECH INC	2021-09-18
Pizotifen Malate	$1.00/5KG	VIP2Y	HUARONG(GUANGDONG) PHARMACEUTICAL CO.,LTD	2025-10-29
Sitravatinib malate	$2500.00/100mg	VIP4Y	TargetMol Chemicals Inc.	2025-10-27

TargetMol Chemicals Inc.

2YR

United States

Since: 2011-01-07
Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA

INQUIRY

HomePage | About Us | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Product Catalog | Links | Privacy | Terms | Product Manufacturers | New Products
All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.