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Postion:Product Catalog >STAT3-IN-11
STAT3-IN-11
  • STAT3-IN-11

STAT3-IN-11 NEW

Price $149
Package 1mg
Min. Order:
Supply Ability: 10g
Update Time: 2025-04-27

Product Details

Product Name: STAT3-IN-11 CAS No.: 2503096-50-0
Purity: 98.3% Supply Ability: 10g
Release date: 2025/04/27

Product Introduction

Bioactivity

NameSTAT3-IN-11
DescriptionSTAT3-IN-11 is a selective STAT3 inhibitor with inhibitory effects on phosphorylation of the STAT3pTyr705 site and phosphorylation of Survivin.STAT3-IN-11 promotes apoptosis in cancer cells and is a candidate compound for the treatment of cancer.
In vitroSTAT3-IN-11 (2.5-10μM, 6 hours) dose-dependently inhibits phosphorylation of STAT3 at the pTyr705 site stimulated by IL-6 in MDA-MB-231 cells. However, it does not affect the phosphorylation of upstream kinases such as p-JAK2 and p-Src, nor the phosphorylation of STAT1, a STAT subtype.
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 80 mg/mL (238.55 mM), Sonication is recommended.
KeywordsSTAT3 | Apoptosis
Inhibitors RelatedStavudine | 5-Fluorouracil | Acetylcysteine | Myricetin | Dextran sulfate sodium salt (MW 4500-5500) | Sodium 4-phenylbutyrate | L-Ascorbic acid | L-Glutamic acid | Metronidazole | Tributyrin | L-Ascorbic acid sodium salt | Salicylic acid

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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