Stylopine hydrochloride NEW
| Price | $48 | $98 | $163 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-12-22 |
Product Details
| Product Name: Stylopine hydrochloride | CAS No.: 96087-21-7 |
| Purity: 99.04% | Supply Ability: 10g |
| Release date: 2025/12/22 |
Product Introduction
Bioactivity
| Name | Stylopine hydrochloride |
| Description | Stylopine is a protoberberine-type alkaloid that has potential biological activities, including anti-inflammatory activity. |
| In vitro | Stylopine is a major component of the leaf of Chelidonium majus L. (Papaveraceae), which has been used for the removal of warts, papillomas and condylomas, as well as the treatment of liver disease, in oriental countries.?Stylopine per se had no cytotoxic effect in unstimulated RAW 264.7 cells, but concentration-dependently reduced nitric oxide (NO), prostaglandin E2 (PGE2), tumor necrosis factor-alpha (TNF-alpha) and interleukin-1beta (IL-1beta), and the IL-6 production and cyclooxygenase-2 (COX-2) activity caused by the LPS stimulation.?The levels of inducible nitric oxide synthase (iNOS) and COX-2 protein expressions were markedly suppressed by stylopine in a concentration dependent manner.?Suggest that stylopine suppress the NO and PGE2 production in macrophages by inhibiting the iNOS and COX-2 expressions.?These biological activities of stylopine may contribute to the anti-inflammatory activity of Chelidonium majus. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 3.6 mg/mL (10.01 mM), Sonication is recommended. |
| Keywords | Tetrahydrocoptisine | Stylopine hydrochloride | Stylopine Hydrochloride | Inos | Inhibitor | inhibit | COX-2 | Corydalis | anti-parasitic | alkaloid | (±)-Stylopine |
| Inhibitors Related | Flubendazole | Kojic acid | Urethane | Acetaminophen | Hydroxychloroquine | Metronidazole | 2-Amino-2-methyl-1-propanol | Doxycycline | Fenpyroximate | Methylene Blue trihydrate | Trometamol | Coumaran |
| Related Compound Libraries | Anti-Tumor Natural Product Library | Traditional Chinese Medicine Monomer Library | Bioactive Compound Library | Pain-Related Compound Library | Selected Plant-Sourced Compound Library | Anti-Inflammatory Traditional Chinese Medicine Compound Library | Antiparasitic Natural Product Library | Natural Product Library for HTS | Anti-infective Natural Product Library | Anti-Aging Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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