Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride NEW
| Price | Get Latest Price |
| Package | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-08-21 |
Product Details
| Product Name: Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride | CAS No.: 2245697-84-9 |
| Supply Ability: 10g | Release date: 2025/08/21 |
Product Introduction
Bioactivity
| Name | Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride |
| Description | Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate, incorporates a cereblon ligand derived from Thalidomide and a 3-unit PEG linker. This compound is specifically designed for use in PROTAC technology, which utilizes small molecules to induce protein degradation [1]. |
| In vitro | Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride, incorporating a Degron (E3 ubiquitin ligase) and a connecting linker, is crucial in PROTAC technology. It binds to the targeting ligand to facilitate the degradation of specific proteins, including BRD4, BRD2, and BRD3[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | Thalidomide-O-amido-PEG3-C2-NH2 Hydrochloride | Thalidomide-O-amido-PEG-3-C2-NH2 hydrochloride | ThalidomideOamidoPEG3C2NH2 hydrochloride | Thalidomide O amido PEG3 C2 NH2 hydrochloride | Cereblon |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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