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Postion:Product Catalog >Transglutaminase 3/TGM3 Protein, Human, Recombinant (His)
Transglutaminase 3/TGM3 Protein, Human, Recombinant (His)
  • Transglutaminase 3/TGM3 Protein, Human, Recombinant (His)

Transglutaminase 3/TGM3 Protein, Human, Recombinant (His) NEW

Price $696
Package 100μg
Min. Order:
Supply Ability: 10g
Update Time: 2025-08-29

Product Details

Product Name: Transglutaminase 3/TGM3 Protein, Human, Recombinant (His) Supply Ability: 10g
Release date: 2025/08/29

Product Introduction

Bioactivity

NameTransglutaminase 3/TGM3 Protein, Human, Recombinant (His)
DescriptionTransglutaminases (TGase) are a family of calcium-dependent acyl-transfer enzymes ubiquitously expressed in mammalian cells and responsible for catalyzing covalent cross-links between proteins or peptides. Transglutaminase 3 (TGM3) is a member of a family of Ca2+-dependent enzymes that catalyze covalent cross-linking reactions between proteins or peptides. TGM3 isoform is widely expressed and is important for epithelial barrier formation. It is a zymogen, requiring proteolysis for activity. Calcium-activated TGM3 can bind, hydrolyze, and is inhibited by GTP, despite lacking structural homology with other GTP binding proteins. TGM3 displays a diffuse cytoplasmic distribution in vitro consistent with its proposed role in the early phase of cornified cell envelope assembly in the cytoplasm. TGM3-driven specific isopeptide bonds between intermediate filaments and KAPs participate to the progressive scaffolding of the hair shaft. Additionally, TGM3 may be a novel prognostic biomarker for esophageal squamous cell carcinoma (ESCC).
Storagestore at low temperature | Shipping with blue ice/Shipping at ambient temperature.
KeywordsUHS-2 | UHS 2

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

4YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, USA
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