Trichlormethiazide sodium NEW
| Price | $2140 | $2785 | $3520 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-10-27 |
Product Details
| Product Name: Trichlormethiazide sodium | CAS No.: 91996-54-2 |
| Supply Ability: 10g | Release date: 2025/10/27 |
Product Introduction
Bioactivity
| Name | Trichlormethiazide sodium |
| Description | Trichlormethiazide sodium is an orally active thiazide diuretic with antihypertensive effects. In an acute renal failure rats model, it increases urine volume (UV), Na and K excretion, and tends to improve creatinine clearance (CCRE). |
| In vivo | Trichlormethiazide, administered at 1 mg/kg orally once, was observed to elevate urinary volume along with sodium and potassium excretion in rats. A higher dose of 10 mg/kg, administered intravenously every day for 5 days, substantially decreased mean arterial pressure (MAP) within 24 hours in male Sprague-Dawley rats (weighing 350-450 g) with high salt intake receiving angiotensin II, without affecting MAP in other groups. This compound showed pronounced effects in increasing potassium excretion in normal male Wistar rats (weighing 170-300 g) and enhanced urinary volume, sodium, and potassium excretion in rats with cisplatin-induced acute renal failure (ARF). Conversely, when administered at 10 mg/kg intravenously daily for 15 days, it effectively lowered MAP in rats subjected to a combination of angiotensin II and high salt intake, indicating its potential benefits in managing hypertension under specific dietary conditions. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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