Product Details
| Product Name:
XL 999 |
CAS No.:
705946-27-6 |
| Purity:
98.24% |
Supply Ability:
10g |
| Release date:
2025/12/03 |
Product Introduction
Bioactivity
| Name | XL 999 |
| Description | Tyrosine kinase-IN-1 is a multi-targeted tyrosine kinase inhibitor that acts on KDR, Flt-1, FGFR1, and PDGFRα with IC50 values of 4 nM, 20 nM, 4 nM, and 2 nM, respectively. |
| In vivo | Tyrosine kinase-IN-1 demonstrates a reasonable pharmacokinetic profile [AUC(0–∞)=1.9, t1/2=4.6 h] and possesses favorable oral bioavailability (F=63%) in rats. |
| Storage | keep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 62.5 mg/mL (140.28 mM), Sonication is recommended.
|
| Keywords | VEGFR | Vascular endothelial growth factor receptor | Tyrosine kinase-IN-1 | Tyrosine kinaseIN1 | Tyrosine kinase IN 1 | Platelet-derived growth factor receptor | PDGFRα | PDGFR | KDR | Inhibitor | inhibit | FLT1 | Fibroblast growth factor receptor | FGFR1 | FGFR |
| Inhibitors Related | Gilteritinib | Amlexanox | Sorafenib | Ferulic Acid | glycine | Nintedanib esylate | Regorafenib | Ethyl cinnamate | Formononetin | Lenvatinib | Pazopanib | Albendazole |
| Related Compound Libraries | Anti-Lung Cancer Compound Library | Reprogramming Compound Library | Anti-Pancreatic Cancer Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Kinase Inhibitor Library | Tyrosine Kinase Inhibitor Library | Angiogenesis related Compound Library | Inhibitor Library | Anti-Prostate Cancer Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$32.00/10kg |
VIP4Y
|
Hebei Dangtong Import and export Co LTD
|
2023-03-03 |
|
|
$1820.00/25mg |
VIP2Y
|
TargetMol Chemicals Inc.
|
2025-07-26 |
United States