Product Details
| Product Name:
UC-857993 |
CAS No.:
487001-04-7 |
| Supply Ability:
10g |
Release date:
2025/10/27 |
Product Introduction
Bioactivity
| Name | UC-857993 |
| Description | UC-857993, a selective SOS1-Ras inhibitor (Kd=14.7 μM, His6-SOS1cat), effectively suppresses catalytic activity. In addition to inhibiting ERK and Ras activation, it also hampers the growth of mouse embryonic fibroblasts (MEFs). |
| In vitro | Imidacloprid (0, 10, and 20 μM ; 4-6 days) can reduce insulin-stimulated glucose uptake in adipocytes (3T3-L1), hepatocytes (HepG2), and myotubes (C2C12) cell culture models. Treatment with imidacloprid inhibits phosphorylation of protein kinase B (AKT) and ribosomal S6 kinase (S6K).[3] |
| In vivo | Imidacloprid(0, 5, 10, 20 mg/kg/day ; oral ; female rats) shows mild pathological changes in the brain, liver, and kidneys of rats.[4] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | UC-857993 | UC857993 | UC 857993 |
| Inhibitors Related | TBHQ | Adagrasib | RMC-9805 | Lidocaine | 4-Methylbenzylidene camphor | Astragaloside IV | MRTX1133 | RMC-6236 | Lidocaine hydrochloride | Tauroursodeoxycholate | β-Glycerophosphate disodium salt hydrate | Nisin Z |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
You may like
-
CAS:116679-69-7
$1520.00 / 25mg
-
CAS:927822-45-5
$1980.00 / 50mg
-
CAS:178870-32-1
$1480.00 / 50mg
Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$68.00/1mg |
VIP4Y
|
TargetMol Chemicals Inc.
|
2025-11-10 |
|
|
$30.00/1mg |
VIP6Y
|
TargetMol Chemicals Inc.
|
2025-11-09 |
|
|
$99.00/1EA |
|
Amikon Limited
|
2018-11-08 |
United States