ZLN 024 hydrochloride NEW
| Price | $44 | $91 | $163 |
| Package | 10mg | 25mg | 50mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-12-03 |
Product Details
| Product Name: ZLN 024 hydrochloride | CAS No.: 1883548-91-1 |
| Purity: 99.86% | Supply Ability: 10g |
| Release date: 2025/12/03 |
Product Introduction
Bioactivity
| Name | ZLN 024 hydrochloride |
| Description | ZLN 024 hydrochloride is an AMPK allosteric activator and stimulates the inactive α1 subunit truncations α1 (1-394) and α1 (1-335) but not α1 (1-312). |
| In vitro | ZLN 024 hydrochloride increases the activity of α1β1γ1 by 1.5-fold and has an EC50 of 0.42 µM, and it increases the activity of α2β1γ1 by 1.7-fold with an EC50 of 0.95 µM. ZLN 024 hydrochloride also directly activates recombinant AMPK α1β2γ1, by 1.7-fold with an EC50 of 1.1 µM; and AMPK α2β2γ1, by 1.6-fold with an EC50 of 0.13 µM. ZLN 024 hydrochloride directly activates recombinant AMPK α1β1γ1 and its homolog α2β1γ1 in a concentration-dependent manner[1]. |
| In vivo | In C57BKS db/db mice, ZLN 024 hydrochloride(15 mg/kg/day; oral) improves glucose tolerance after 4 weeks of treatment. ZLN 024 hydrochloride reduces the fasting blood glucose by 15%. Liver tissue weight, triacylglycerol and the total cholesterol content a |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (5.53 mM), Sonication is recommended. DMSO : 45 mg/mL (124.42 mM), Sonication is recommended. H2O : < 0.1 mg/mL (insoluble) |
| Keywords | ZLN-024 Hydrochloride | ZLN024 Hydrochloride | ZLN-024 | ZLN024 | ZLN 024 Hydrochloride | ZLN 024 hydrochloride | ZLN 024 | Inhibitor | inhibit | AMPK α2β2γ1 | AMPK α2β1γ1 | AMPK α1β2γ1 | AMPK α1β1γ1 | AMPK | AMP-activated protein kinase |
| Inhibitors Related | Sesamol | Adenosine monophosphate | Adenosine 5'-monophosphate monohydrate | Chromium(III) acetate | Methyl cinnamate | Metformin hydrochloride | D-Arabinopyranose | Tranexamic acid | Chitosan oligosaccharide | Isovaleric acid | Danthron | D-Arabinose |
| Related Compound Libraries | Bioactive Compound Library | Antidepressant Compound Library | Kinase Inhibitor Library | Glutamine Metabolism Compound Library | Anti-Ovarian Cancer Compound Library | Pyroptosis Compound Library | Neuroprotective Compound Library | Metabolism Compound Library | Anti-Aging Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | AMPK-Targeted Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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