ZZL-7 / Ac-Ala-Val-OMe NEW
Price | Get Latest Price |
Package | 1g |
Min. Order: | 1g |
Supply Ability: | 20 tons |
Update Time: | 2024-03-29 |
Product Details
Product Name: ZZL-7 / Ac-Ala-Val-OMe | CAS No.: 99141-91-0 |
Min. Order: 1g | Purity: 99% min |
Supply Ability: 20 tons | Release date: 2024/03/29 |
English name: L-Valine, N-acetyl-L-alanyl-, methyl ester (9CI)
CAS number: 99141-91-0
Molecular formula: C11H20N2O4
Molecular weight: 244.29
ZZL-7 is a fast-acting antidepressant that enhances 5-HT (serotonin) signaling in forebrain circuits. ZZL-7 disrupts the interaction between the 5-HT transporter (SERT) and neuronal nitric oxide synthase (nNOS) in the dorsal raphe nucleus (DRN), reduces extracellular 5-HT concentration and downregulates 5-HT1A receptor auto-activity in the DRN. This reduced auto-inhibition enables increase in firing frequency of serotonergic neurons in the DRN and increases in 5-HT release in the medial hippocampus. ZZL-7 readily crosses the blood-brain barrier.
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