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Nimesulide(51803-78-2)

Nimesulide(51803-78-2)
Product IdentificationBack to Contents
【Product Name】

Nimesulide
【Synonyms】

1-(Benzothiazol-2-yl)-1,3-dimethylurea
Aulin
Mesulid
N-(4-Nitro-2-phenoxyphenyl)methanesulfonamide
N-(4-Nitro-2-phenoxy-phenyl)methanesulfonamide
Nimesulide
【CAS】

51803-78-2
【Formula】

C13H12N2O5S
【Molecular Weight】

308.31
【EINECS】

257-431-4
【RTECS】

PB0970000
【RTECS Class】

Drug; Reproductive Effector; Human Data
【Merck】

12,6640
【Beilstein/Gmelin】

2421175
【Beilstein Reference】

6-13
Physical and Chemical PropertiesBack to Contents
【Solubility in water】

10 mg/L (20 C)
【Melting Point】

143 - 144
【Boiling Point】

442
【Vapor Pressure】

5E-8 (25 C)
【Density】

1.476 g/cm3
【pKa/pKb】

8.49 (pKa)
【Heat Of Vaporization】

69.9 kJ/mol
【Usage】

Treatment of hyperpyrexia related to respiratory infections.
First Aid MeasuresBack to Contents
【Ingestion】

If swallowed, wash out mouth with water provided person is conscious. Call a physician.
【Inhalation】

If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.
【Skin】

In case of contact, immediately wash skin with soap and copious amounts of water.
【Eyes】

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.
Handling and StorageBack to Contents
【Storage】

Keep tightly closed.
Hazards IdentificationBack to Contents
【Inhalation】

May be harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.
【Skin】

May cause skin irritation. May be harmful if absorbed through the skin.
【Eyes】

May cause eye irritation.
【Ingestion】

May be harmful if swallowed.
【Hazards】

Emits toxic fumes under fire conditions.
【EC Risk Phrase】

50/53
【EC Safety Phrase】

60 61
【UN (DOT)】

3077
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

Protective gloves. Chemical safety goggles.
【Respirators】

Wear dust mask.
【Exposure Effects】

Avoid contact and inhalation.
【Poison Class】

4
Fire Fighting MeasuresBack to Contents
【Flash Point】

221
【Fire Fighting】

Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
【Fire Potential】

May burn but does not ignite readily.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability and ReactivityBack to Contents
【Stability】

Stable at normal temperatures and pressures.
【Incompatibilities】

Strong oxidizing agents.
【Decomposition】

Carbon monoxide, Carbon dioxide, Nitrogen oxides, Sulfur oxides.
【Combustion Products】

Fire may produce irritating, corrosive and/or toxic gases.
Transport InformationBack to Contents
【UN Number】

3077
【Hazard Class】

9
【Packing Group】

III
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