| Product Identification | Back to Contents | 【Product Name】
N-Chloroethyl-N-ethylaniline | 【Synonyms】
2-(N-Ethylanilino)ethyl chloride
Ethyl(chloroethyl)aniline
N-(2-Chloroethyl)-N-ethylaniline | 【CAS】
92-49-9 | 【Formula】
C10H14ClN | 【Molecular Weight】
183.7 | 【EINECS】
202-159-3 | 【RTECS】
BX1300000 | 【RTECS Class】
Other | 【Beilstein/Gmelin】
1073025 | 【Beilstein Reference】
3-12-00-00263 |
| Physical and Chemical Properties | Back to Contents | 【Appearance】
Needles from alcohol. | 【Solubility in water】
Insoluble | 【Melting Point】
45.5-46.5 | 【Boiling Point】
163 - 164 (42 torr) | 【pKa/pKb】
6.69 (pKb) | 【Usage】
A metabolite of alkoxyaniline mustards in microsomal suspensions. |
| First Aid Measures | Back to Contents | 【Ingestion】
The possible benefit of early removal of some ingested material by cautious gastric lavage must be weighed against potential complications of bleeding or perforation. Activated charcoal activated charcoal binds most toxic agents and can decrease their systemic absorption if administered soon after ingestion. Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents. | 【Inhalation】
Time is of the essence - immediately remove the victim from the contaminated area, stabilize the hemodynamic status, provide oxygen and manage airway aggressively. | 【Skin】
There is no specific antidote once the mustard gas has reached the cells. Decontaminate by washing with water and neutralizing with a 2.5 Percent solution of sodium thiosulfate. Oral prednisone, topical antiseptic solutions and a regimen of vitamin e may be beneficial; promethazine or antihistamines have been used. Antimicrobial ointments should be applied to blisters. Treat systematic effects as outlined in the inhalation exposure section. The us military previously used the m2581a skin decontamination kit containing towelettes soaked with phenol+hydroxide and chloramine. This has been replaced with the resins ambergard xe-555 and xe-556. Expedients which may be used include powders such as talcum powder, flour, and fuller's earth. Dilute (0.5 Percent) hypochlorite (bleach) solutions can also be used. | 【Eyes】
Irrigate thoroughly with water and neutralize with a 2.5 percent solution of sodium thiosulfate. Treat systematic effects as outlined in the inhalation exposure section. |
| Handling and Storage | Back to Contents | 【Storage】
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage. | 【Handling】
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood. |
| Hazards Identification | Back to Contents | 【Inhalation】
Irritation or ulceration of the respiratory tract can occur from inhalation; lesions may be fatal. Respiratory impairment may be delayed and severe. Pulmonary edema may occur. | 【Skin】
Severe irritation was produced from doses as low as 65 mcg in humans. The first effect on skin is redness, similar to a sunburn. | 【Eyes】
Severe eye irritant inducing edema, burning discomfort, photophobia, tearing, and/or blepharospasm. Ulceration of the cornea and/or BLINDNESS ranging from burning discomfort to destruction of the eyeball may occur after severe exposure. Local ischemia/thrombosis with delayed hemorrhage has developed several days after exposure. The mechanism of action is not known, but it could be immune system mediated. | 【Ingestion】
Nausea, vomiting, diarrhea and epigastric pain can be caused either by ingestion or systemic absorption. | 【Hazards】
Containers may explode when heated. | 【UN (DOT)】
2018 |
| Exposure Controls/Personal Protection | Back to Contents | 【Personal Protection】
Wear appropriate protective gloves, clothing and goggles. | 【Respirators】
Wear positive pressure self-contained breathing apparatus (SCBA). | 【Exposure Effects】
Dyspnea and paroxysmal cough are common. Fever may occur. Dizziness, malaise, anorexia, lethargy can occur after acute exposure. Intellectual dullness is common. Probable human teratogen. |
| Fire Fighting Measures | Back to Contents | 【Fire Fighting】
Small Fires: Dry chemical, carbon dioxide or water spray. Large Fires: Water spray, fog or regular foam. | 【Fire Potential】
Combustible material: may burn but does not ignite readily. |
| Accidental Release Measures | Back to Contents | 【Small spills/leaks】
Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Cover with plastic sheet to prevent spreading. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS. |
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