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21-Desoxybetamethasone(382-67-2)

21-Desoxybetamethasone(382-67-2)
Product IdentificationBack to Contents
【Product Name】

21-Desoxybetamethasone
【Synonyms】

9-Fluoro-11b,21-dihydroxy-16a-methylpregna-1,4-diene-3,20-dione
【CAS】

382-67-2
【Formula】

C22H29FO4
【Molecular Weight】

376.47
【EINECS】

206-845-3
【RTECS】

TU3834000
【RTECS Class】

Reproductive Effector; Hormone
【Merck】

12,2975
【Beilstein/Gmelin】

2228097
【Beilstein Reference】

6-08
Physical and Chemical PropertiesBack to Contents
【Solubility in water】

Insoluble
【Melting Point】

217
【Vapor Pressure】

2E-13 (25 C)
【pKa/pKb】

12.80 (pKa)
【Heat Of Vaporization】

92.9 kJ/mol
【Usage】

A topical steroid used to treat inflammation caused by a number of conditions such as allergic reactions, eczema, and psoriasis.
First Aid MeasuresBack to Contents
【Ingestion】

If swallowed, wash out mouth with water provided person is conscious. Call a physician.
【Inhalation】

If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.
【Skin】

In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
【Eyes】

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.
Hazards IdentificationBack to Contents
【Inhalation】

Material is irritating to mucous membranes and upper respiratory tract.
【EC Risk Phrase】

20/21/22 36/37/38 40 43
【EC Safety Phrase】

22 26 36
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

Compatible chemical-resistant gloves. Chemical safety goggles.
【Respirators】

Government approved respirator.
【Exposure Effects】

Harmful. Harmful by inhalation, in contact with skin and if swallowed. Irritating to eyes, respiratory system and skin. Limited evidence of a carcinogenic effect. May cause sensitization by skin contact. Target organ(s): Pituitary. Poss
Fire Fighting MeasuresBack to Contents
【Flash Point】

276
【Fire Fighting】

Extinguish using Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability and ReactivityBack to Contents
【Stability】

Stable at normal temperatures and pressures.
【Decomposition】

Carbon monoxide, Carbon dioxide, Hydrogen fluoride.
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