ChemicalBook >>1,2-Dichloropropane>>1,2-Dichloropropane(78-87-5)

1,2-Dichloropropane(78-87-5)

1,2-Dichloropropane(78-87-5)
Product IdentificationBack to Contents
【Product Name】

1,2-Dichloropropane
【Synonyms】

2H-4,16a-Epoxybenzo[7,8]fluoreno[2,1-b]quinolizine, cevane-3,4,12,14,16,17,20-heptol deriv.
3-Veratroylveracevine
4,9-Epoxycevane-3,4,12,14,16,17,20-heptol 3-(3,4-dimethoxybenzoate)
Cevane-3,4,12,14,16,17,20-heptol, 4,9-epoxy-, 3-(3,4-dimethoxybenzoate), (3B,4A,16B)-
Dichloropropane
Propylene dichloride
Veratrine
【CAS】

71-62-5
【CAS】

78-87-5
【Formula】

C36H51NO11
【Formula】

C3H6Cl2
【Molecular Weight】

112.99
【Molecular Weight】

673.8
【EINECS】

200-758-4
【EINECS】

201-152-2
【RTECS】

TX9625000
【RTECS】

YX5600000
【RTECS Class】

Natural Product
【RTECS Class】

Agricultural Chemical and Pesticide; Tumorigen; Mutagen; Reproductive Effector; Primary Irritant
【Merck】

12,10087
【Merck】

12,8039
【Beilstein/Gmelin】

1718880
【Beilstein/Gmelin】

78875
【Beilstein Reference】

4-01-00-00195
【Beilstein Reference】

5-21-13-00709
【EC Index Number】

602-020-00-0
【EC Class】

Highly flammable; Harmful
Physical and Chemical PropertiesBack to Contents
【Appearance】

Colorless liquid with a sweet odor.
【Appearance】

Yellowish-white, amorphous powder.
【Solubility in water】

soluble
【Solubility in water】

0.27 g / 100 ml
【Melting Point】

-100
【Melting Point】

180
【Boiling Point】

95 - 96
【Vapor Pressure】

54 (25 C)
【Density】

1.158 g/cm3 (20 C)
【Partition Coefficient】

2.28
【Heat Of Vaporization】

32.0 kJ/mol
【Usage】

A na ion channel activator. Veratridine acts at neurotoxin receptor site 2 and preferentially binds to activated na ion channels causing persistent activation.
【Usage】

Oil and fat solvent, insecticide, nematicide.
【Vapor Density】

3.9
【Odor threshold】

23 ppm
【Refractive Index】

1.4388 (20 C)
First Aid MeasuresBack to Contents
【Ingestion】

Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
【Ingestion】

Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended.
【Ingestion】

Severe nausea and vomiting with epigastric and substernal pain may occur.
【Inhalation】

Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
【Inhalation】

If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.
【Inhalation】

Dyspnea may occur.
【Skin】

Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
【Skin】

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
【Skin】

Sweating has been reported.
【Eyes】

Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.
【Eyes】

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Handling and StorageBack to Contents
【Storage】

Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area.
【Storage】

Store at -20 C in a dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
【Handling】

Wash thoroughly after handling. Use only in a well ventilated area. Ground and bond containers when transferring material. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
【Handling】

All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Hazards IdentificationBack to Contents
【Inhalation】

Inhalation of high concentrations may cause central nervous system effects characterized by headache, dizziness, unconsciousness and coma. Causes respiratory tract irritation. May cause liver and kidney damage. May cause anemia. Vapors may cause dizziness or suffocation. May cause cardiac abnormalities. Symptoms of inhalation include: anorexia, abdominal pain, vomiting, blood abnormalities, and hematuria.
【Skin】

Causes skin irritation. Prolonged and/or repeated contact may cause defatting of the skin and dermatitis. May be absorbed through the skin.
【Eyes】

Causes moderate eye irritation. Vapors cause eye irritation. May cause eye injury.
【Ingestion】

May be harmful if swallowed. May cause effects similar to those of acute inhalation. Causes gastrointestinal tract irritation.
【Hazards】

Liquid is heavier than water. Vapor is heavier than air (vapor-air density at 100 deg f, 1.4) and may travel considerable distance to source of ignition and flash back.
【EC Risk Phrase】

R 11 20/22
【EC Safety Phrase】

S 16 24
【UN (DOT)】

1279
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
【Personal Protection】

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
【Respirators】

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
【Respirators】

Use NIOSH/MSHA approved respirator appropriate for exposure of concern.
【Exposure Effects】

salivation, muscular weakness, and syncope may occur. Coma may occur in severe cases. Headache, aphasia, and seizures are uncommon effects of intoxication.
【Exposure Effects】

Chronic inhalation and ingestion may cause effects similar to those of acute inhalation and ingestion.
【Exposure limit(s)】

OSHA PEL: TWA 75 ppm (350 mg/m3) NIOSH REL: Ca See Appendix A NIOSH IDLH: Potential occupational carcinogen 400 ppm
【Poison Class】

3
Fire Fighting MeasuresBack to Contents
【Flash Point】

4
【Autoignition】

557
【Fire Fighting】

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.
【Fire Fighting】

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Extinguishing media: For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. For large fires, use water spray, fog, or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Water may be ineffective. Do NOT use straight streams of water.
【Upper exp. limit】

14.5
【Lower exp. limit】

3.4
【Fire Potential】

Flammable liquid and vapor. Vapors may travel to ignition source and flash back. Does not catch fire readily in industrial applications.
【Fire Potential】

Slight fire hazard.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. A vapor suppressing foam may be used to reduce vapors.
【Small spills/leaks】

Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces.
Stability and ReactivityBack to Contents
【Stability】

No data.
【Incompatibilities】

Oxidizing agents, acids, , aluminum, orthodichlorobenzene + ethylene dichloride + aluminum. Will attack some forms of plastic, rubber, and coatings.
【Stability】

Stable under normal temperatures and pressures.
【Incompatibilities】

Strong oxidizing agents.
【Decomposition】

Hydrogen chloride, phosgene, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
【Combustion Products】

Toxic and irritating gases may be generated.
Transport InformationBack to Contents
【UN Number】

1279
【Hazard Class】

3
【Packing Group】

II
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