| Product Identification | Back to Contents | 【Product Name】
Methacryloyl chloride | 【Synonyms】
2-Methylprop-2-enoyl chloride
Methacrylic acid chloride
Methacrylyl chloride | 【CAS】
920-46-7 | 【Formula】
C4H5ClO | 【Molecular Weight】
104.54 | 【EINECS】
213-058-9 | 【RTECS】
OZ5791000 | 【RTECS Class】
Other | 【Beilstein/Gmelin】
878175 | 【Beilstein Reference】
4-02-00-01537 |
| Physical and Chemical Properties | Back to Contents | 【Appearance】
Colorless to yellow liquid. | 【Solubility in water】
Slightly soluble | 【Melting Point】
-60 | 【Boiling Point】
95 | 【Vapor Pressure】
44 (25 C) | 【Density】
1.0562 g/cm3 (20 C) | 【Partition Coefficient】
1.61 | 【Heat Of Vaporization】
33.6 kJ/mol | 【Usage】
A hydrogel with 80% water absorption was obtained from reaction of 2-hydroxyethyl methacrylate, containing small amounts of ethylene glycol dimethacrylate with the reaction product of poly(vinylpyrrolidinone) & methacryloyl chloride contact lenses. | 【Refractive Index】
1.4433 |
| First Aid Measures | Back to Contents | 【Ingestion】
The possible benefit of early removal of some ingested material by cautious gastric lavage must be weighed against potential complications of bleeding or perforation. Activated charcoal activated charcoal binds most toxic agents and can decrease their systemic absorption if administered soon after ingestion. Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents. | 【Inhalation】
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols. | 【Skin】
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists. Treat dermal irritation or burns with standard topical therapy. Patients developing dermal hypersensitivity reactions may require treatment with systemic or topical corticosteroids or antihistamines. | 【Eyes】
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility. |
| Handling and Storage | Back to Contents | 【Storage】
Keep away from sources of ignition. Store in a cool, dry place. Store in a tightly closed container. Refrigerator/flammables. | 【Handling】
Wash thoroughly after handling. Use spark-proof tools and explosion proof equipment. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Avoid contact with heat, sparks and flame. Use only in a chemical fume hood. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. |
| Hazards Identification | Back to Contents | 【Ingestion】
Irritation or burns of the esophagus or gastrointestinal tract may follow ingestion. | 【Inhalation】
May cause irritation of the respiratory tract with burning pain in the nose and throat, coughing, wheezing, shortness of breath and pulmonary edema. Causes chemical burns to the respiratory tract. Inhalation may be fatal as a result of spasm, inflammation, edema of the larynx and bronchi, chemical pneumonitis and pulmonary edema. | 【Skin】
Dermal irritation and burning may occur. Sensitization is predicted. | 【Eyes】
Causes severe eye burns. Lachrymator. | 【EC Risk Phrase】
R 11 22 26 34 37 | 【EC Safety Phrase】
S 16 26 28 36/37/39 45 | 【UN (DOT)】
3286 |
| Exposure Controls/Personal Protection | Back to Contents | 【Personal Protection】
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots. | 【Respirators】
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary. |
| Fire Fighting Measures | Back to Contents | 【Flash Point】
4 | 【Fire Fighting】
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire. |
| Accidental Release Measures | Back to Contents | 【Small spills/leaks】
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container.Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. |
| Stability and Reactivity | Back to Contents | 【Stability】
Stable at room temperature in closed containers under normal storage. | 【Incompatibilities】
Strong oxidizing agents. | 【Decomposition】
Hydrogen chloride, phosgene, carbon monoxide, carbon dioxide, chloride fumes. |
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