| Product Identification | Back to Contents | 【Product Name】
3alpha,7beta-Dihydroxy-6beta-cholan-24-oic acid | 【Synonyms】
17b-(1-Methyl-3-carboxypropyl)etiocholane-3a,7b-diol
3a,7b-Dihydroxy-5b-cholanic acid
7b-Hydroxylithocholic acid
Actigall
Ursodesoxycholic acid
Ursofalk | 【CAS】
128-13-2 | 【Formula】
C24H40O4 | 【Molecular Weight】
392.57 | 【EINECS】
204-879-3 | 【RTECS】
FZ2000000 | 【RTECS Class】
Drug; Mutagen; Reproductive Effector | 【Merck】
12,10026 | 【Beilstein/Gmelin】
3219888 | 【Beilstein Reference】
4-10-00-01604 |
| Physical and Chemical Properties | Back to Contents | 【Appearance】
White powder. | 【Solubility in water】
Insoluble | 【Melting Point】
205 | 【Boiling Point】
547 | 【Vapor Pressure】
3E-14 (25 C) | 【pKa/pKb】
4.76 (pKa) | 【Partition Coefficient】
4.66 | 【Heat Of Vaporization】
95.0 kJ/mol | 【Usage】
Anticholelithic. Used in the treatment of gallstone disease. It is taken by mouth to dissolve the gallstones. |
| First Aid Measures | Back to Contents | 【Ingestion】
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. | 【Inhalation】
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. | 【Skin】
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. | 【Eyes】
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. |
| Handling and Storage | Back to Contents | 【Storage】
Store in a tightly closed container. Store in a cool, dry area away from incompatible substances. | 【Handling】
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. |
| Hazards Identification | Back to Contents | 【Ingestion】
May cause irritation of the digestive tract. | 【Inhalation】
May cause respiratory tract irritation. | 【Skin】
May cause skin irritation. | 【Eyes】
May cause eye irritation. |
| Exposure Controls/Personal Protection | Back to Contents | 【Personal Protection】
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin. | 【Respirators】
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use. |
| Fire Fighting Measures | Back to Contents | 【Flash Point】
299 | 【Fire Fighting】
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use dry chemical, carbon dioxide, or appropriate foam. |
| Stability and Reactivity | Back to Contents | 【Incompatibilities】
Oxidizing agents. | 【Stability】
Stable under normal temperatures and pressures. | 【Decomposition】
Carbon monoxide, carbon dioxide, acrid smoke and fumes. |
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