ChemicalBook >>Cinobufotalin>>14,15b-Epoxy-3b,5a,16b-trihydroxy-5b,20(22)-bufadienolide 16-acetate(1108-68-5)

14,15b-Epoxy-3b,5a,16b-trihydroxy-5b,20(22)-bufadienolide 16-acetate(1108-68-5)

14,15b-Epoxy-3b,5a,16b-trihydroxy-5b,20(22)-bufadienolide 16-acetate(1108-68-5)
Product IdentificationBack to Contents
【Product Name】

14,15b-Epoxy-3b,5a,16b-trihydroxy-5b,20(22)-bufadienolide 16-acetate
【Synonyms】

14,15-Epoxy-14H-cyclopenta[a]phenanthrene, bufa-20,22-dienolide deriv.
5-b-Bufa-20,22-dienolide, 14,15-b-epoxy-3-b,5,16-b-trihydroxy, 16-acetate
Bufa-20,22-dienolide, 16- (acetyloxy)-14,15-epoxy-3,5-dihydroxy-, (3.beta.,5.beta.,15.beta.,16.beta.)-
【CAS】

1108-68-5
【Formula】

C26H34O7
【Molecular Weight】

458.55
【RTECS】

EI2991000
【Merck】

12,2367
Physical and Chemical PropertiesBack to Contents
【Solubility in water】

.73
【Melting Point】

259 - 262
【Boiling Point】

627
【Vapor Pressure】

2.3E-18 (25 C)
【Density】

1.34 kJ/mol
【pKa/pKb】

14.67 (pKa)
【Partition Coefficient】

.87
【Heat Of Vaporization】

106/4 kJ/mol
First Aid MeasuresBack to Contents
【Ingestion】

If swallowed, wash out mouth with water provided person is conscious. Call a physician.
【Inhalation】

If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
【Skin】

In case of contact, immediately wash skin with soap and copious amounts of water. Remove contaminated clothing and shoes. Call a physician.
【Eyes】

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.
Handling and StorageBack to Contents
【Storage】

Store at 2 - 8 C.
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

Compatible chemical-resistant gloves. Chemical safety goggles. Protective clothing.
【Respirators】

Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Where risk assessment shows air-purifying respirators are appropriate use a full-face particle respirator type N100 (US) or type P3 (EN 143) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator.
【Exposure Effects】

May be fatal if inhaled, swallowed, or absorbed through skin. Toad venoms are cardioactive and can cause death by disturbing the normal heart rhythm. The mucous membrane that lines the mouth is a means of introducing the venom into the bloodstream. (Venomous Animals and Their Venoms, vol. II: Bucherl, W. Editor).
Fire Fighting MeasuresBack to Contents
【Flash Point】

210
【Fire Fighting】

Extinguish with water spray, carbon dioxide, dry chemical powder or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

Carefully sweep up and remove. Place in appropriate container. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability and ReactivityBack to Contents
【Incompatibilities】

Moisture.
【Stability】

Stable at normal temperatures and pressures.
【Decomposition】

Oxides of carbon.
Transport InformationBack to Contents
【UN Number】

2811
【Hazard Class】

6.1
【Packing Group】

I
Hazards IdentificationBack to Contents
【Hazards】

Emits toxic fumes under fire conditions.
【EC Risk Phrase】

26/27/28
【EC Safety Phrase】

22 36/37/39 45
【UN (DOT)】

2811
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