ChemicalBook >>Ampicillin>>Ampicillin

Ampicillin

Ampicillin
Product IdentificationBack to Contents
【Product Name】

Ampicillin
【Synonyms】

(2S,5R,6R)-6-((R)-2-amino-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
1,9-Nonanediamine
Alpen
Amfipen
Aminobenzylpenicillin
D(-)-alpha-Aminobenzylpenicillin
D-(-)-alpha-Aminopenicillin
Nonane-1,9-diamine
【CAS】

646-24-2
【CAS】

69-53-4
【Formula】

C16H19N3O4S
【Formula】

C9H22N2
【Molecular Weight】

158.29
【Molecular Weight】

349.41
【EINECS】

200-709-7
【EINECS】

211-470-3
【RTECS】

XH8350000
【RTECS Class】

Tumorigen; Drug; Mutagen; Reproductive Effector; Human Data
【Merck】

12,628
【Beilstein/Gmelin】

1737533
【Beilstein/Gmelin】

629178
【Beilstein Reference】

4-04-00-01364
【EC Class】

irritant
Physical and Chemical PropertiesBack to Contents
【Appearance】

White solid.
【Appearance】

White, crystalline powder. Odorless or has a faint odor characteristic of the penicillins.
【Solubility in water】

1 gm dissolves in about 90 ml
【Solubility in water】

575 g/L (20 C)
【Melting Point】

35 - 38
【Melting Point】

202
【Boiling Point】

258
【Vapor Pressure】

0.014 (25 C)
【pKa/pKb】

3.03 (pKb)
【pKa/pKb】

2.61 (pKa)
【Heat Of Vaporization】

49.6 kJ/mol
【Usage】

Antibiotic.
First Aid MeasuresBack to Contents
【Ingestion】

Get medical aid. Wash mouth out with water.
【Ingestion】

Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended.
【Inhalation】

If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.
【Inhalation】

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
【Inhalation】

Causes respiratory tract irritation.
【Skin】

Causes skin irritation.
【Skin】

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
【Skin】

Remove contaminated clothing. Wash exposed area with soap and water. If symptoms persist, seek medical attention. Launder clothing before reuse.
【Eyes】

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
【Eyes】

If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention.
【Eyes】

Causes eye irritation.
Handling and StorageBack to Contents
【Storage】

Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
【Storage】

Store in a cool, dry place. Store in a tightly closed container.
【Handling】

All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
【Handling】

Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Use only in a chemical fume hood.
Hazards IdentificationBack to Contents
【Ingestion】

May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
【Skin】

Contact dermatitis may occur due to hypersensitivity reactions.
【Ingestion】

Diarrhea, nausea, vomiting, and abdominal pain may occur.
【Hazards】

When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.
【EC Risk Phrase】

R 34
【EC Safety Phrase】

S 26 36/37/39 45
【UN (DOT)】

3265
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
【Personal Protection】

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
【Respirators】

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
【Respirators】

Use NIOSH/MSHA approved respirator appropriate for exposure of concern.
【Exposure Effects】

drowsiness, myoclonus, seizures, and coma may occur following large iv doses. Neurological side effects may be more common in patients with impaired renal function.
Fire Fighting MeasuresBack to Contents
【Flash Point】

110
【Autoignition】

285
【Fire Fighting】

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.
【Fire Fighting】

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.
【Fire Potential】

Combustible material: may burn but does not ignite readily.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces.
【Small spills/leaks】

Vacuum or sweep up material and place into a suitable disposal container.
Stability and ReactivityBack to Contents
【Disposal Code】

3
【Incompatibilities】

Acids, acid chlorides, acid anhydrides, oxidizing agents.
【Stability】

No data.
【Stability】

Stable under normal temperatures and pressures. Absorbs carbon dioxide from the air.
【Incompatibilities】

Strong oxidizing agents.
【Decomposition】

Nitrogen oxides, carbon monoxide, carbon dioxide.
【Combustion Products】

Fire may produce irritating, corrosive and/or toxic gases.
Transport InformationBack to Contents
【UN Number】

3265
【Hazard Class】

8
【Packing Group】

I; II; III
【HS Code】

2921 29 00
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