ChemicalBook >>2,2'-Azobis(2-methylpropionitrile)>>Azodiisobutyrodinitrile(78-67-1)

Azodiisobutyrodinitrile(78-67-1)

Azodiisobutyrodinitrile(78-67-1)
Product IdentificationBack to Contents
【Product Name】

Azodiisobutyrodinitrile
【Synonyms】

Echinomycin A
N-[3,11,13,16,24,26-Hexamethyl-27-methylsulfanyl-2,5,9,12,15,18,22,25-octaoxo-4,17-dipropan-2-yl-8-(quinoxaline-2-carbonylamino)-6,19-dioxa-28-thia-3,10,13,16,23,26-hexazabicyclo[12.12.3]nonacos-21-yl]quinoxaline-2-carboxamide
NSC-526417
Quinomycin A
S-426-S (Lepetit)
【CAS】

512-64-1
【Formula】

C51H64N12O12S2
【Molecular Weight】

1101.27
【RTECS】

JW5250000
【Merck】

12,3545
【Beilstein/Gmelin】

78671
【Beilstein Reference】

4-27-00-09726
Physical and Chemical PropertiesBack to Contents
【Appearance】

Very faintly beige powder.
【Solubility in water】

Insoluble
【Melting Point】

217 - 218
【Density】

1.41 g/cm3 (20 C)
【pKa/pKb】

9.38 (pKa)
【Partition Coefficient】

-.67
【Usage】

A cytotoxic polypeptide quinoxaline antibiotic isolated from streptomyces echinatus that binds to dna and inhibits rna synthesis.
First Aid MeasuresBack to Contents
【Ingestion】

If swallowed, wash out mouth with water provided person is conscious. Call a physician immediately.
【Inhalation】

If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
【Skin】

In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
【Eyes】

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.
Handling and StorageBack to Contents
【Storage】

Keep container tightly closed. Store at 2 - 8 C.
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

Wear self-contained breathing apparatus, rubber boots, and heavy rubber gloves.
【Respirators】

Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Where risk assessment shows air-purifying respirators are appropriate use a full-face particle respirator type N99 (US) or type P2 (EN 143) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator.
【Exposure Effects】

Toxic. May cause heritable genetic damage. Toxic by inhalation, in contact with skin and if swallowed. Nausea, headache, and vomiting. Reversible liver enzyme abnormalities.
Fire Fighting MeasuresBack to Contents
【Fire Fighting】

Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes. Extinguishing media: Water spray. Carbon dioxide, dry chemical powder or appropriate foam.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability and ReactivityBack to Contents
【Stability】

Stable at normal temperatures and pressures.
【Incompatibilities】

Strong oxidizing agents.
【Decomposition】

Oxides of carbon, nitrogen and sulfur.
【Combustion Products】

Emits toxic fumes under fire conditions.
Transport InformationBack to Contents
【UN Number】

3462
【Hazard Class】

6.1
【Packing Group】

II
Hazards IdentificationBack to Contents
【EC Risk Phrase】

R: 23/24/25 46
【EC Safety Phrase】

S: 36/37/39 45 53
【UN (DOT)】

3462
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