ChemicalBook >>TRIS hydrochloride>>2-Amino-2-(hydroxymethyl)-1,3-propanediol hydrochloride(1185-53-1)

2-Amino-2-(hydroxymethyl)-1,3-propanediol hydrochloride(1185-53-1)

2-Amino-2-(hydroxymethyl)-1,3-propanediol hydrochloride(1185-53-1)
Product IdentificationBack to Contents
【Product Name】

2-Amino-2-(hydroxymethyl)-1,3-propanediol hydrochloride
【Synonyms】

2-Amino-2-(hydroxymethyl)-1,3-propanediol hydrochloride
2-Amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride
Tris (hydroxymethyl) aminomethane hydrochloride
Trizma hydrchloride
【CAS】

1185-53-1
【Formula】

C4H12ClNO3
【Molecular Weight】

157.6
【EINECS】

214-684-5
【Merck】

12,9902
【Beilstein/Gmelin】

3675235
【Beilstein Reference】

0-04-00-00303
Physical and Chemical PropertiesBack to Contents
【Appearance】

White powder.
【Solubility in water】

Soluble
【Melting Point】

149
【pKa/pKb】

8.1(at 25℃) (pKa)
First Aid MeasuresBack to Contents
【Ingestion】

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
【Inhalation】

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
【Skin】

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
【Eyes】

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Handling and StorageBack to Contents
【Storage】

Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
【Handling】

Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Hazards IdentificationBack to Contents
【Inhalation】

The toxicological properties of this substance have not been fully investigated. Inhalation of dust may cause respiratory tract irritation.
【Skin】

No information regarding skin irritation and other potential effects was found.
【Eyes】

No information regarding eye irritation and other potential effects was found.
【Ingestion】

The toxicological properties of this substance have not been fully investigated.
【EC Safety Phrase】

S 22 24/25
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
【Respirators】

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
【Exposure Effects】

The toxicological properties of this substance have not been fully investigated.
Fire Fighting MeasuresBack to Contents
【Fire Fighting】

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing media: Use agent most appropriate to extinguish fire.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Avoid generating dusty conditions.
Stability and ReactivityBack to Contents
【Disposal Code】

3
【Incompatibilities】

Oxidizing agents.
【Stability】

Stable under normal temperatures and pressures.
【Decomposition】

Nitrogen oxides, bromine.
Transport InformationBack to Contents
【HS Code】

2922 19 80
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