ChemicalBook >>Chlortalidone>>Chlorthalidone(77-36-1)

Chlorthalidone(77-36-1)

Chlorthalidone(77-36-1)
Product IdentificationBack to Contents
【Product Name】

Chlorthalidone
【Synonyms】

1-keto-3-(3'-Sulfamyl-4'-chlorophenyl)-3-hydroxyisoindoline
2-Chloro-5-(3-hydroxy-1-oxoisoindol-3-yl)benzenesulfonamide
3-Hydroxy-3-[4-chloro-3-sulfamylphenyl]phthalimidine
Benzenesulfonamide, 2-chloro-5-(2,3-dihydro-1-hydroxy-3-oxo-1H-isoindol-1-yl)-
Demi-Regroton
Natriuran
【CAS】

77-36-1
【Formula】

C14H11ClN2O4S
【Molecular Weight】

338.77
【EINECS】

201-022-5
【RTECS】

DB1556000
【RTECS Class】

Reproductive Effector; Human Data
【Merck】

12,2246
【Beilstein/Gmelin】

312295
【Beilstein Reference】

5-22-07-00602
Physical and Chemical PropertiesBack to Contents
【Appearance】

White to yellowish-white crystalline powder. Odorless.
【Solubility in water】

Slightly soluble
【Melting Point】

179
【pKa/pKb】

4.43 (pKb)
【Usage】

Therap cat (vet): diuretic.
First Aid MeasuresBack to Contents
【Ingestion】

Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended.
【Inhalation】

If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.
【Skin】

Remove contaminated clothing. Wash exposed area with soap and water. If symptoms persist, seek medical attention. Launder clothing before reuse.
【Eyes】

If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention.
Handling and StorageBack to Contents
【Storage】

Keep in airtight container.
【Handling】

Use in hood. Wear protective equipment. Do not raise dust.
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
【Respirators】

None is normally required. If needed, a NIOSH/MSHA aproved air supplied respirator or dust respirator is advised.
【Exposure Effects】

Irritation. Possible allergic reation to dust. May cause dryness of mouth, increased thirst, irregular heartbeat, mood changes, muscle cramps, pain, nausea, vomiting, tiredness, weakness, weak pulse.
Fire Fighting MeasuresBack to Contents
【Fire Fighting】

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

Wear approved protective equipment. Vacuum or sweep up spill. Avoid dust creation. Place spillage in appropriate container for disposal.
Stability and ReactivityBack to Contents
【Stability】

Stable under normal temperatures and pressures.
【Incompatibilities】

Strong oxidizing agents.
【Decomposition】

Toxic fumes.
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