ChemicalBook >>Aprotinin>>Aprotinin(9087-70-1)

Aprotinin(9087-70-1)

Aprotinin(9087-70-1)
Product IdentificationBack to Contents
【Product Name】

Aprotinin
【Synonyms】

Bovine pancreatic trypsin inhibitor
Bovine trypsin inhibitor
Kunitz protease inhibitor
Trypsin inhibitor
Trypsin inhibitor, pancreatic basic
Zymofren
【CAS】

9087-70-1
【Formula】

C284H432N84O79S7
【Molecular Weight】

6511.53
【EINECS】

232-994-9
【RTECS】

YN5080000
【RTECS Class】

Reproductive Effector
【Merck】

12,796
【Beilstein/Gmelin】

NA
Physical and Chemical PropertiesBack to Contents
【Appearance】

White powder.
【Usage】

Proteolytic inhibitor in radioimmunoassays of polypeptide hormones.
First Aid MeasuresBack to Contents
【Ingestion】

Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
【Inhalation】

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration.
【Skin】

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
【Eyes】

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Handling and StorageBack to Contents
【Storage】

Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Refrigerator (approx 4 C).
【Handling】

Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Hazards IdentificationBack to Contents
【Inhalation】

May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. Inhalation of high concentrations may result in bronchospasm.
【Skin】

May cause skin irritation. May cause erythema, and edema with crusting and scaling.
【Eyes】

May cause eye irritation.
【Ingestion】

May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated.
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
【Respirators】

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
【Exposure Effects】

Reproductive effects have been reported in animals.
Fire Fighting MeasuresBack to Contents
【Fire Fighting】

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Extinguishing media: Substance is noncombustible; use agent most appropriate to extinguish surrounding fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.
Stability and ReactivityBack to Contents
【Incompatibilities】

Oxidizing agents.
【Stability】

Stable at room temperature in closed containers under normal storage and handling conditions.
【Decomposition】

Carbon monoxide, oxides of nitrogen, oxides of sulfur, irritating and toxic fumes and gases, carbon dioxide.
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