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Alfacalcidol(41294-56-8)

Alfacalcidol(41294-56-8)
Product IdentificationBack to Contents
【Product Name】

Alfacalcidol
【Synonyms】

1a-Hydroxyvitamin D3
1-Hydroxycholecalciferol
9,10-Secocholesta-5,7,10(19)-triene-1,3-diol, (1a,3b,5Z,7E)-
【CAS】

41294-56-8
【Formula】

C27H44O2
【Molecular Weight】

400.65
【EINECS】

255-297-1
【RTECS】

VS2851000
【RTECS Class】

Drug; Reproductive Effector
【Merck】

12,4864
【Beilstein/Gmelin】

1916848
【Beilstein Reference】

5-06
Physical and Chemical PropertiesBack to Contents
【Appearance】

Fine white crystals
【Solubility in water】

Insoluble
【Melting Point】

132 - 133
【Vapor Pressure】

2E-13 (25 C)
【pKa/pKb】

13.82 (pKa)
【Heat Of Vaporization】

92.83 kJ/mol
【Usage】

A form of vitamin d. It is converted rapidly in the liver to the active metabolite, 1,25-dihydroxycholecalciferol (calcitriol).
First Aid MeasuresBack to Contents
【Ingestion】

If swallowed, wash out mouth with water provided person is conscious. Call a physician immediately.
【Inhalation】

If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
【Skin】

In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
【Eyes】

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.
Handling and StorageBack to Contents
【Storage】

Keep tightly closed. Store at -20 C
Hazards IdentificationBack to Contents
【Inhalation】

May be fatal if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.
【Skin】

May cause skin irritation. May be fatal if absorbed through skin.
【Eyes】

May cause eye irritation.
【Ingestion】

May be fatal if swallowed.
【Hazards】

Emits toxic fumes under fire conditions.
【EC Risk Phrase】

26/27/28
【EC Safety Phrase】

28 36/37 45
【UN (DOT)】

2811
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

Compatible chemical-resistant gloves.
【Respirators】

Government approved respirator.
【Exposure Effects】

Very toxic by inhalation, in contact with skin and if swallowed.
Fire Fighting MeasuresBack to Contents
【Fire Fighting】

Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
【Fire Potential】

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability and ReactivityBack to Contents
【Stability】

Stable at normal temperatures and pressures.
【Incompatibilities】

Strong oxidizing agents.
【Decomposition】

Carbon monoxide, Carbon dioxide.
【Combustion Products】

Fire may produce irritating, corrosive and/or toxic gases.
Transport InformationBack to Contents
【UN Number】

2811
【Hazard Class】

6.1
【Packing Group】

I
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