| Product Identification | Back to Contents | 【Product Name】
10,10'-Oxybis-10H-phenoxarsine | 【Synonyms】
[(2R,3R,4R,5R)-2-(6-Aminopurin-9-yl)-4-hydroxy-5-(hydroxymethyl)oxolan-3-yl] dihydrogen phosphate
10,10'-Oxybisphenoxyarsine
10-Phenoxarsinin-10-yloxyphenoxarsinine
2'-AMP
Adenosine 2'-monophosphate
Adenosine 2'-monophosphoric acid
Adenosine 2'-phosphate
Adenosine 2'-phosphoric acid
bis(10-Phenoxarsinyl) oxide
bis(10-Phenoxarsyl) oxide
bis(Phenoxarsin-10-yl) ether
Vinadine | 【CAS】
130-49-4 | 【CAS】
58-36-6 | 【Formula】
C10H14N5O7P | 【Formula】
C24H16As2O3 | 【Molecular Weight】
502.23 | 【Molecular Weight】
347.22 | 【EINECS】
200-377-3 | 【EINECS】
204-990-7 | 【RTECS】
AU7480300 | 【RTECS】
SP6800000 | 【RTECS Class】
Other | 【RTECS Class】
Primary Irritant | 【Merck】
12,7095 | 【Beilstein/Gmelin】
55641 | 【Beilstein/Gmelin】
58366 | 【Beilstein Reference】
4-26-00-03612 | 【Beilstein Reference】
2-27-00-00948 |
| Physical and Chemical Properties | Back to Contents | 【Appearance】
A clear light yellow liquid with a mild odor. | 【Appearance】
White powder. | 【Solubility in water】
5 ppm @ 20 C | 【Solubility in water】
Very soluble | 【Melting Point】
184 | 【Melting Point】
187 | 【Density】
1.65 g/cm3 | 【pKa/pKb】
1.83 (pKa) | 【Usage】
Fungicide, microbiocide. |
| First Aid Measures | Back to Contents | 【Ingestion】
Do not induce emesis - dilution: following ingestion and/or prior to gastric evacuation, immediately dilute with 4 to 8 ounces (120 to 240 ml) of milk or water (not to exceed 15 ml/kg in a child). The possible benefit of early removal of some ingested material by cautious gastric lavage must be weighed against potential complications of bleeding or perforation. | 【Ingestion】
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. | 【Inhalation】
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. | 【Inhalation】
If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention. | 【Inhalation】
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. | 【Skin】
May cause skin irritation. | 【Skin】
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. | 【Skin】
Remove all exposed clothing and jewelry taking necessary precautions to prevent secondary exposure to health care providers. Irrigate exposed areas promptly with copious amounts of water for at least 30 minutes. Wash the skin, including hair and nails, vigorously; do repeated soap washings. Discard contaminated clothing. | 【Eyes】
May cause eye irritation. | 【Eyes】
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. | 【Eyes】
If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention. |
| Handling and Storage | Back to Contents | 【Storage】
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage. | 【Storage】
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Deep freeze (below -20 C). | 【Handling】
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. | 【Handling】
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood. |
| Hazards Identification | Back to Contents | 【Ingestion】
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated. | 【Inhalation】
Severe respiratory irritation leading to pulmonary edema would be expected from acute exposure to obpa. Respiratory failure and adult respiratory distress syndrome have occurred in acute arsenic intoxication. | 【Eyes】
Tearing and burns or strong irritation occur to the eyes. A garlic-like odor may be apparent on the breath. | 【Ingestion】
Induction of vomiting is one of the bases for its use as a military agent. Gastroenteritis, sometimes with watery or bloody diarrhea, occurs with acute exposure to arsenic. |
| Exposure Controls/Personal Protection | Back to Contents | 【Personal Protection】
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots. | 【Personal Protection】
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. | 【Respirators】
Use NIOSH/MSHA approved respirator appropriate for exposure of concern. | 【Respirators】
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use. | 【Exposure Effects】
Abnormally low blood pressure and rapid heart rate may develop with acute arsenic poisoning. Toxic delirium and encephalopathy are complications of acute arsenic poisoning; encephalopathy may be permanent. Peripheral neuropathy leading to profound muscular weakness and wasting may be delayed by several weeks after acute exposure; recovery is usually slow or incomplete. No reproductive studies were found for OBPA, but arsenic compounds have been fetotoxic and teratogenic in animals. Arsenic can most likely cross the placenta. One neonatal fatality and several uneventful births have occurred in cases of acute arsenic poisoning in pregnancy. <br>Arsenic is excreted in the breast milk. Lower doses of arsenic have not affected male fertility in animals, but toxic doses have produced effects on the testes. |
| Fire Fighting Measures | Back to Contents | 【Fire Fighting】
(Non-Specific -- Arsenic Compound, Solid, n.o.s.) Stay upwind; keep out of low areas. Wear self-contained (positive pressure if available) breathing apparatus and full protective clothing.(Non-Specific -- Arsenic Compound, Solid, n.o.s.) Small fires: dry chemical, carbon dioxide, water spray, or foam. Large fires: water spray, fog, or foam. Move container from fire area if you can do so without risk. | 【Fire Fighting】
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam. |
| Accidental Release Measures | Back to Contents | 【Small spills/leaks】
Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation. | 【Small spills/leaks】
Keep material out of water sources and sewers. Build dikes to contain flow as necessary. |
| Stability and Reactivity | Back to Contents | 【Incompatibilities】
Incompatible with acids and bases Incompatible with oxidizing agents. | 【Stability】
No data. | 【Incompatibilities】
Oxidizing agents. | 【Stability】
Stable under normal temperatures and pressures. | 【Decomposition】
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, phosphorous fumes. |
|
| Company Name: |
Bide Pharmatech Ltd. |
| Tel: |
400-1647117 15221909166 |
| Fax: |
+86-21-61629029 |
| WebSite: |
www.bidepharm.com |
|