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Sulindac(38194-50-2)

Sulindac(38194-50-2)
Product IdentificationBack to Contents
【Product Name】

Sulindac
【Synonyms】

(Z)-5-Fluoro-2-methyl-1-[p-(methylsulfinyl)benzylidene]indene-3-acetic acid
5-Fluoro-2-methyl-1-[[4-(methylsulfinyl)phenyl]methylene]-1H-indene-3-acetic acid
cis-5-Fluoro-2-methyl-1-[(p-methylsulfinyl)benzylidenyl]indene-3-acetic acid
【CAS】

38194-50-2
【Formula】

C20H17FO3S
【Molecular Weight】

356.42
【EINECS】

253-819-2
【RTECS】

NK8226000
【RTECS Class】

Drug; Reproductive Effector; Human Data
【Merck】

12,9155
【Beilstein/Gmelin】

2951842
【Beilstein Reference】

6-10
Physical and Chemical PropertiesBack to Contents
【Solubility in water】

Insoluble
【Melting Point】

195
【Boiling Point】

582
【Vapor Pressure】

2E-14 (25 C)
【pKa/pKb】

4.22 (pKa)
【Partition Coefficient】

3.42
【Heat Of Vaporization】

91.5 kJ/mol
【Usage】

Nonsteroidal anti-inflammatory; preferential inhibitor of cox-1.
First Aid MeasuresBack to Contents
【Ingestion】

If swallowed, wash out mouth with water provided person is conscious. Call a physician.
【Inhalation】

If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
【Skin】

In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
【Eyes】

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.
Handling and StorageBack to Contents
【Storage】

Keep tightly closed.
Hazards IdentificationBack to Contents
【Inhalation】

May be harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.
【Skin】

May cause skin irritation. May be harmful if absorbed through the skin.
【Eyes】

May cause eye irritation.
【Ingestion】

Harmful if swallowed.
【Hazards】

Emits toxic fumes under fire conditions.
【EC Risk Phrase】

22
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

Compatible chemical-resistant gloves. Chemical safety goggles.
【Respirators】

Government approved respirator.
【Exposure Effects】

Toxic if swallowed. Target organ(s): Liver. G.I. System.
Fire Fighting MeasuresBack to Contents
【Flash Point】

306
【Fire Fighting】

Extinguish using Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability and ReactivityBack to Contents
【Stability】

Stable at normal temperatures and pressures.
【Incompatibilities】

Strong oxidizing agents.
【Decomposition】

Carbon monoxide, Carbon dioxide, Sulfur oxides, Hydrogen fluoride.
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