ChemicalBook >>Sumatriptan>>1-[3-(2-Dimethylaminoethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide(103628-46-2)

1-[3-(2-Dimethylaminoethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide(103628-46-2)

1-[3-(2-Dimethylaminoethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide(103628-46-2)
Product IdentificationBack to Contents
【Product Name】

1-[3-(2-Dimethylaminoethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide
【Synonyms】

3-(2-(Dimethylamino)ethyl)-N-methyl-1H-indole-5-methanesulfonamide
GR-43175
GR-43175X
Imigran
Imitrex
【CAS】

103628-46-2
【Formula】

C14H21N3O2S
【Molecular Weight】

295.41000000000003
【RTECS】

NL9482200
【Merck】

12,9172
【Beilstein/Gmelin】

6930870
Physical and Chemical PropertiesBack to Contents
【Appearance】

Distributed as a 5 - 20% aqueous solution.
【Solubility in water】

Soluble
【Melting Point】

169 - 171
【Boiling Point】

498
【Vapor Pressure】

4.8E-10 (25 C)
【Density】

1.243 g/cm3 (20 C)
【pKa/pKb】

11.31 (pKa)
【Partition Coefficient】

-2.3
【Heat Of Vaporization】

76.6 kJ/mol
【Usage】

A triptan drug including a sulfonamide group.
First Aid MeasuresBack to Contents
【Ingestion】

Never attempt to induce vomiting. Do not attempt to give any solid or liquid by mouth if the exposed subject is unconscious or semi-conscious. Wash out the mouth with water. If the exposed subject is fully conscious, give plenty of water to drink. Obtain medical attention.
【Inhalation】

Physical form suggests that risk of inhalation exposure is negligible.
【Skin】

Using appropriate personal protective equipment, remove contaminated clothing and flush exposed area with large amounts of water. Obtain medical attention if skin reaction occurs, which may be immediate or delayed.
【Eyes】

Wash immediately with clean and gently flowing water. Continue for at least 15 minutes. Obtain medical attention.
Handling and StorageBack to Contents
【Storage】

No storage requirements necessary for occupational hazards. Follow product information storage instructions to maintain efficacy.
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

Protective gloves and clothing. Chemical safety goggles.
【Exposure Effects】

Medical treatment in cases of overexposure should be treated as an overdose of a 5-hydroxytryptamine agonist. Treat according to locally accepted protocols. For additional guidance, refer to the current prescribing information or to the local poison control information centre.
Fire Fighting MeasuresBack to Contents
【Fire Fighting】

For single units (packages): No special requirements needed. For larger amounts (multiple packages/pallets) of product: Since toxic, corrosive or flammable vapors might be evolved from fires involving this product and associated packaging, self contained breathing apparatus and full protective equipment are recommended for firefighters. If possible, contain and collect firefighting water for later disposal.
【Fire Potential】

Product is non combustable.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

Collect and place it in a suitable, properly labeled container for recovery or disposal.
Company Name: Shaanxi Istare Biotechnology Co., Ltd.
Tel: 029-81530825 18682931470
Fax:
WebSite: www.istarepharm.com/
Company Name: J & K SCIENTIFIC LTD.
Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
WebSite: http://www.jkchemical.com
Company Name: 3B Pharmachem (Wuhan) International Co.,Ltd.
Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
WebSite: https://www.chemicalbook.com/ShowSupplierProductsList13285/0.htm
Company Name: Chembest Research Laboratories Limited
Tel: 021-20908456
Fax: 021-58180499
WebSite: http://www.BioChemBest.com
Company Name: JinYan Chemicals(ShangHai) Co.,Ltd.
Tel: 13817811078
Fax: 86-021-50426522,50426273
WebSite: www.jingyan-chemical.com
Company Name: Syntechem Co.,Ltd
Tel:
Fax: E-Mail Inquiry
WebSite: www.syntechem.com
Company Name: Sinopharm Chemical Reagent Co,Ltd.
Tel: 86-21-63210123
Fax: 86-21-63290778 86-21-63218885
WebSite: www.reagent.com.cn
Company Name: Beijing Yisiyan Technology Research Center
Tel: 010-56645598 13366904824
Fax: 01062230033
WebSite: http://www.bjkaida.cn