ChemicalBook >>Cimetidine>>2-Cyano-1-methyl-3-(2-(((5-methylimidazol-4-yl)methyl)thio)ethyl)guanidine(51481-61-9)

2-Cyano-1-methyl-3-(2-(((5-methylimidazol-4-yl)methyl)thio)ethyl)guanidine(51481-61-9)

2-Cyano-1-methyl-3-(2-(((5-methylimidazol-4-yl)methyl)thio)ethyl)guanidine(51481-61-9)
Product IdentificationBack to Contents
【Product Name】

2-Cyano-1-methyl-3-(2-(((5-methylimidazol-4-yl)methyl)thio)ethyl)guanidine
【Synonyms】

1-Cyano-2-methyl-3-(2-(((5-methyl-4-imidazolyl)methyl)thio)ethyl)guanidine
2-Cyano-1-methyl-3-(2-(((5-methylimidazol-4-yl)methyl)thio)ethyl)guanidine
Eureceptor
Gastromet
N-Cyano-N'-methyl-N''-(2-(((5-methyl-1h-imidazol-4-yl)methyl)thio)ethyl)guanidine
Tagamet
【CAS】

51481-61-9
【Formula】

C10H16N6S
【Molecular Weight】

252.34
【EINECS】

257-232-2
【RTECS】

MF0035500
【RTECS Class】

Tumorigen; Drug; Mutagen; Reproductive Effector; Human Data
【Merck】

12,2337
【Beilstein/Gmelin】

888260
Physical and Chemical PropertiesBack to Contents
【Appearance】

White crystals with a slight sulfur-mercaptan odor.
【Solubility in water】

1.14% @ 37 C
【Melting Point】

152 - 154
【Density】

1.31 g/cm3
【pKa/pKb】

6.8 (pKa)
【Partition Coefficient】

.4
【Usage】

Inhibits gastric acid secretion, as well as pepsin and gastrins output.
First Aid MeasuresBack to Contents
【Ingestion】

DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician.
【Inhalation】

IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used.
【Skin】

IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.
【Eyes】

First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.
Handling and StorageBack to Contents
【Storage】

Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
【Handling】

All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Hazards IdentificationBack to Contents
【Inhalation】

Respiratory depression may occur.
【Skin】

Occupational dermatitis, vasculitis, urticaria, stevens-johnson syndrome, ten, and psoriasis have been reported.
【Ingestion】

Respiratory depression may occur.
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
【Respirators】

Wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter.
【Exposure Effects】

confusion, disorientation or delirium with dizziness, drowsiness, and slurred speech, have been reported. Visual hallucinations, CNS depression, seizures, and coma have occurred. Dystonia and chorea has been reported.
Fire Fighting MeasuresBack to Contents
【Fire Fighting】

Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher.
【Fire Potential】

This material is probably combustible.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

If you spill this chemical, FIRST REMOVE ALL SOURCES OF IGNITION. You should then dampen the solid spill material with 60-70% methanol, then transfer the dampened material to a suitable container. Use absorbent paper dampened with methanol to pick up any remaining material. Your contaminated clothing and absorbent paper should be sealed in a vapor-tight plastic bag for eventual disposal. Solvent-wash contaminated surfaces with 60-70% methanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.
Stability and ReactivityBack to Contents
【Stability】

No data.
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