ChemicalBook >>Dexamethasone>>9alpha-Fluoro-11beta,17alpha,21-trihydroxy-16alpha-methylpregn-1,4-diene-3,20-dione(50-02-2)

9alpha-Fluoro-11beta,17alpha,21-trihydroxy-16alpha-methylpregn-1,4-diene-3,20-dione(50-02-2)

9alpha-Fluoro-11beta,17alpha,21-trihydroxy-16alpha-methylpregn-1,4-diene-3,20-dione(50-02-2)
Product IdentificationBack to Contents
【Product Name】

9alpha-Fluoro-11beta,17alpha,21-trihydroxy-16alpha-methylpregn-1,4-diene-3,20-dione
【Synonyms】

Aphthasolone
Deltafluorene
Gammacorten
Prednisolone F
Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17,21-trihydroxy-16-methyl-, (11b,16a)-
Visumetazone
【CAS】

50-02-2
【Formula】

C22H29FO5
【Molecular Weight】

392.47
【EINECS】

200-003-9
【RTECS】

TU3980000
【RTECS Class】

Drug; Mutagen; Reproductive Effector; Human Data; Hormone
【Merck】

12,2986
【Beilstein/Gmelin】

2066651
Physical and Chemical PropertiesBack to Contents
【Appearance】

Odorless white to off-white crystalline powder with a slightly bitter taste.
【Solubility in water】

Insoluble
【Melting Point】

268 - 271
【pKa/pKb】

12.14 (pKa)
【Usage】

Medication.
First Aid MeasuresBack to Contents
【Ingestion】

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid immediately.
【Inhalation】

Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
【Skin】

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
【Eyes】

First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.
Handling and StorageBack to Contents
【Storage】

Store in a cool, dry place. Store in a tightly closed container.
【Handling】

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with skin and eyes. Avoid ingestion and inhalation. Use only in a chemical fume hood.
Hazards IdentificationBack to Contents
【Inhalation】

May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
【Skin】

Causes skin irritation.
【Eyes】

Causes eye irritation.
【Ingestion】

May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

If Tyvek-type disposable protective clothing is not worn during handling of this chemical, wear disposable Tyvek-type sleeves taped to your gloves.
【Respirators】

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
【Exposure Effects】

seizures have been reported following pulse methylprednisolone therapy.
Fire Fighting MeasuresBack to Contents
【Fire Fighting】

Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. A water spray may also be used.
【Fire Potential】

This material is probably combustible.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

Vacuum or sweep up material and place into a suitable disposal container.
Stability and ReactivityBack to Contents
【Stability】

Has not been fully evaluated.
【Incompatibilities】

Strong oxidizing agents.
【Decomposition】

Hydrogen chloride, carbon monoxide, oxides of nitrogen, carbon dioxide.
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