| Product Identification | Back to Contents | 【Product Name】
5-Azacytidine | 【Synonyms】
1,3,5-Triazin-2(1H)-one, 4-amino-1-b-D-ribofuranosyl-
Antibiotic U 18496
Azacytidine
s-Triazin-2(1H)-one, 4-amino-1-b-D-ribofuranosyl-
Vidaza | 【CAS】
320-67-2 | 【Formula】
C8H12N4O5 | 【Molecular Weight】
244.21 | 【EINECS】
206-280-2 | 【RTECS】
XZ3017500 | 【RTECS Class】
Tumorigen; Drug; Mutagen; Reproductive Effector; Human Data; Primary Irritant | 【Merck】
12,923 | 【Beilstein/Gmelin】
620461 |
| Physical and Chemical Properties | Back to Contents | 【Appearance】
White crystalline powder. | 【Solubility in water】
Very soluble | 【Melting Point】
235 | 【Boiling Point】
478 | 【pKa/pKb】
13.69 (pKa) | 【Partition Coefficient】
-1.8 | 【Usage】
Used in the treatment of myelodysplastic syndrome. |
| First Aid Measures | Back to Contents | 【Ingestion】
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately. | 【Inhalation】
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. | 【Skin】
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Remove contaminated clothing and shoes. | 【Eyes】
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. |
| Handling and Storage | Back to Contents | 【Storage】
Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Deep freeze (below -20 C). | 【Handling】
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. |
| Hazards Identification | Back to Contents | 【Inhalation】
Inhalation of dust may cause respiratory tract irritation. | 【Skin】
Causes skin irritation. | 【Eyes】
Dust may cause mechanical irritation. | 【Ingestion】
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause blood abnormalities. |
| Exposure Controls/Personal Protection | Back to Contents | 【Personal Protection】
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. | 【Respirators】
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary. | 【Exposure Effects】
May cause cancer in humans. |
| Fire Fighting Measures | Back to Contents | 【Fire Fighting】
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam. | 【Fire Potential】
This material is probably combustible. |
| Stability and Reactivity | Back to Contents | 【Stability】
Stable under normal temperatures and pressures. | 【Incompatibilities】
Strong oxidizing agents. | 【Decomposition】
Carbon monoxide, oxides of nitrogen, carbon dioxide. |
|
| Company Name: |
MIDECO |
| Tel: |
023-68625073 15723208759 |
| Fax: |
|
| WebSite: |
www.midecopharm.com/ |
| Company Name: |
J & K SCIENTIFIC LTD. |
| Tel: |
010-82848833 400-666-7788 |
| Fax: |
86-10-82849933 |
| WebSite: |
http://www.jkchemical.com |
|