| Product Identification | Back to Contents | 【Product Name】
Metolazone | 【Synonyms】
2-Methyl-3-(o-tolyl)-6-sulfamyl-7-chloro-1,2,3,4-tetrahydro-4-quinazolinone
6-Quinazolinesulfonamide, 7-chloro-1,2,3,4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo-
Mykrox
Normelan
Xuret
Zaroxolyn | 【CAS】
17560-51-9 | 【Formula】
C16H16ClN3O3S | 【Molecular Weight】
365.84 | 【EINECS】
241-539-3 | 【RTECS】
VA1700000 | 【RTECS Class】
Drug; Reproductive Effector; Human Data | 【Merck】
12,6231 | 【Beilstein/Gmelin】
965506 | 【Beilstein Reference】
5-25-09-00212 |
| Physical and Chemical Properties | Back to Contents | 【Appearance】
White crystalline powder crystalline powder. | 【Solubility in water】
Insoluble | 【Melting Point】
257 - 263 | 【pKa/pKb】
10.00 (pKa) | 【Partition Coefficient】
4.1 | 【Usage】
Major uses include medication. |
| First Aid Measures | Back to Contents | 【Ingestion】
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. | 【Inhalation】
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. | 【Skin】
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. | 【Eyes】
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. |
| Handling and Storage | Back to Contents | 【Storage】
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from light. | 【Handling】
Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Store protected from light. |
| Hazards Identification | Back to Contents | 【Ingestion】
May cause irritation of the digestive tract. May cause nausea and vomiting. | 【Inhalation】
May cause respiratory tract irritation. | 【Skin】
May cause skin irritation. | 【Eyes】
May cause eye irritation. |
| Exposure Controls/Personal Protection | Back to Contents | 【Personal Protection】
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. | 【Respirators】
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary. |
| Fire Fighting Measures | Back to Contents | 【Fire Fighting】
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire use water spray, dry chemical, carbon dioxide, or appropriate foam. |
| Accidental Release Measures | Back to Contents | 【Small spills/leaks】
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation. |
| Stability and Reactivity | Back to Contents | 【Incompatibilities】
Oxidizing agents. | 【Stability】
Stable at room temperature in closed containers under normal storage and handling conditions. | 【Decomposition】
Hydrogen chloride, nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, sulfur oxides (SOx), including sulfur oxide and sulfur dioxide. |
|
| Company Name: |
Energy Chemical |
| Tel: |
021-021-58432009 400-005-6266 |
| Fax: |
021-58436166 |
| WebSite: |
http://www.energy-chemical.com |
| Company Name: |
Jia Xing Isenchem Co.,Ltd |
| Tel: |
0573-85285100 18627885956 |
| Fax: |
0573-85285100 |
| WebSite: |
https://www.chemicalbook.com/ShowSupplierProductsList14265/0.htm |
|