| Product Identification | Back to Contents | 【Product Name】
5-(Dithiolan-3-yl)valeric acid | 【Synonyms】
1,2-Dithiolane-3-pentanoic acid, (+/-)-
1,2-Dithiolane-3-valeric acid, (+/-)
5-(Dithiolan-3-yl)pentanoic acid
DL-1,2-Dithiolane-3-valeric acid
DL-6-Thioctic acid
DL-alpha-Lipoic acid | 【CAS】
1077-28-7 | 【Formula】
C8H14O2S2 | 【Molecular Weight】
206.31 | 【EINECS】
214-071-2 | 【RTECS】
JP1192000 | 【RTECS Class】
Other | 【Merck】
12,9462 | 【Beilstein/Gmelin】
81853 | 【Beilstein Reference】
5-19-07-00237 |
| Physical and Chemical Properties | Back to Contents | 【Appearance】
Light yellow to yellow powder. | 【Solubility in water】
Very soluble | 【Melting Point】
59 - 60 | 【Boiling Point】
363 | 【Vapor Pressure】
3E-6 (25 C) | 【Density】
1.343 g/cm3 | 【pKa/pKb】
4.75 (pKa) | 【Partition Coefficient】
2.16 | 【Heat Of Vaporization】
66.8 kJ/mol | 【Usage】
L form is an essential cofactor for many enzyme complexes. |
| First Aid Measures | Back to Contents | 【Ingestion】
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately. | 【Inhalation】
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. | 【Skin】
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. | 【Eyes】
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. |
| Handling and Storage | Back to Contents | 【Storage】
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. | 【Handling】
Wash thoroughly after handling. Use only in a well ventilated area. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. |
| Hazards Identification | Back to Contents | 【Ingestion】
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated. | 【Inhalation】
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. | 【Skin】
May cause skin irritation. The toxicological properties of this material have not been fully investigated. | 【Eyes】
May cause eye irritation. The toxicological properties of this material have not been fully investigated. | 【EC Risk Phrase】
R 22 36/37/38 | 【EC Safety Phrase】
S 26 36/37/39 |
| Exposure Controls/Personal Protection | Back to Contents | 【Personal Protection】
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. | 【Respirators】
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary. |
| Fire Fighting Measures | Back to Contents | 【Flash Point】
173 | 【Fire Fighting】
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam. |
| Accidental Release Measures | Back to Contents | 【Small spills/leaks】
Clean up spills immediately, using the appropriate protective equipment. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Avoid generating dusty conditions. Provide ventilation. |
|
|