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ChemicalBook >>S-(-)-Carbidopa>>3-(3,4-Dihydroxyphenyl)-2-hydrazinyl-2-methyl-propanoic acid(28860-95-9)

3-(3,4-Dihydroxyphenyl)-2-hydrazinyl-2-methyl-propanoic acid(28860-95-9)

3-(3,4-Dihydroxyphenyl)-2-hydrazinyl-2-methyl-propanoic acid(28860-95-9)
Product IdentificationBack to Contents
【Product Name】

3-(3,4-Dihydroxyphenyl)-2-hydrazinyl-2-methyl-propanoic acid
【Synonyms】

Hydrazino-a-methyldopa
L-3-(3,4-Dihydroxyphenyl)-2-methyl-2-hydrazinopropionic acid
L-a-Hydrazino-a-methyl-b-(3,4-dihydroxyphenyl)propionic acid
L-alpha-Methyldopahydrazine
N-Aminomethyldopa
S-(-)-a-Hydrazino-3,4-dihydroxy-2-methylbenzenepropanoic acid
【CAS】

28860-95-9
【Formula】

C10H16N2O5
【Molecular Weight】

244.25
【EINECS】

249-271-9
【RTECS】

MW5298000
【RTECS Class】

Drug; Mutagen; Reproductive Effector
【Merck】

12,1843
【Beilstein/Gmelin】

657532
【Beilstein Reference】

5-15
Physical and Chemical PropertiesBack to Contents
【Solubility in water】

Very soluble
【Melting Point】

206 - 208
【Boiling Point】

419
【Vapor Pressure】

5E-12 (25 C)
【pKa/pKb】

3.40 (pKa)
【Partition Coefficient】

.46
【Heat Of Vaporization】

84.6 kJ/mol
【Usage】

Peripheral inhibitor ofl-aromatic amino acid decarboxylase. When administered simultaneously withl-dopa, it prevents extracerebral conversion to dopamine.
First Aid MeasuresBack to Contents
【Ingestion】

If swallowed, wash out mouth with water provided person is conscious. Call a physician.
【Inhalation】

If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
【Skin】

In case of contact, immediately wash skin with soap and copious amounts of water.
【Eyes】

In case of contact, immediately flush eyes with copious amounts of water for at least 15 minutes.
Handling and StorageBack to Contents
【Storage】

Keep tightly closed. Store in a cool dry place. Store at -20 C
Hazards IdentificationBack to Contents
【Inhalation】

Material may be irritating to mucous membranes and upper respiratory tract.
【Skin】

May cause skin irritation.
【Eyes】

May cause eye irritation.
【Hazards】

Emits toxic fumes under fire conditions.
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

Compatible chemical-resistant gloves. Chemical safety goggles.
【Respirators】

Government approved respirator.
【Exposure Effects】

Avoid contact and inhalation.
Fire Fighting MeasuresBack to Contents
【Fire Fighting】

Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability and ReactivityBack to Contents
【Incompatibilities】

Strong oxidizing agents.
【Decomposition】

Carbon monoxide, Carbon dioxide, Nitrogen oxides.
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