| Product Identification | Back to Contents | 【Product Name】
Ethyl 2-(4-chlorophenoxy)-2-methylpropionate | 【Synonyms】
2-(P-chlorophenoxy)-2-methylpropionic*acid ethyl
Antilipid
Ateculon
Ethyl 2-(4-chlorophenoxy)-2-methylpropionate
Ethyl clofibrate
Phenoxyisobutyricacidethylester | 【CAS】
637-07-0 | 【Formula】
C12H15ClO3 | 【Molecular Weight】
242.7 | 【EINECS】
211-277-4 | 【RTECS】
UE9480000 | 【RTECS Class】
Tumorigen; Drug; Mutagen; Reproductive Effector; Human Data | 【Merck】
12,2436 | 【Beilstein/Gmelin】
1913459 | 【Beilstein Reference】
4-06-00-00851 |
| Physical and Chemical Properties | Back to Contents | 【Appearance】
Oil. Faint characteristic odor. | 【Solubility in water】
insoluble | 【Boiling Point】
148 | 【Density】
1.138-1.144 g/cm3 (20 C) | 【Usage】
Agent to lower plasma very-low-density-lipoprotein concn, agent to lower concn of plasma triglycerides. | 【Refractive Index】
1.505 (19 C) |
| First Aid Measures | Back to Contents | 【Ingestion】
Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended. | 【Inhalation】
If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention. | 【Skin】
Remove contaminated clothing. Wash exposed area with soap and water. If symptoms persist, seek medical attention. Launder clothing before reuse. | 【Eyes】
If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention. |
| Handling and Storage | Back to Contents | 【Storage】
Clofibrate liquid-filled capsules should be stored in well-closed, light-resistant containers, at a temperature less than 40C. Preferably at 15-30C; freezing of the liquid-filled capsules should be avoided. | 【Handling】
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood. |
| Hazards Identification | Back to Contents | 【Skin】
Various rashes and alopecia have been reported. | 【Ingestion】
Ausea, vomiting, constipation, dyspepsia, diarrhea, and flatulence occur transiently in approximately 10% of patients. Epigastric pain has been reported as a frequent side effect and cholelithiasis is increased. |
| Exposure Controls/Personal Protection | Back to Contents | 【Personal Protection】
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots. | 【Respirators】
Use NIOSH/MSHA approved respirator appropriate for exposure of concern. | 【Exposure Effects】
with therapeutic use - fatigue, weakness, drowsiness, dizziness, and headache have been reported during clofibrate therapy. Clofibrate and Fenofibrate are classified as FDA Pregnancy Category C. |
| Fire Fighting Measures | Back to Contents | 【Flash Point】
110 | 【Fire Fighting】
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire. |
| Accidental Release Measures | Back to Contents | 【Small spills/leaks】
Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces. |
|
| Company Name: |
J & K SCIENTIFIC LTD. |
| Tel: |
010-82848833 400-666-7788 |
| Fax: |
86-10-82849933 |
| WebSite: |
http://www.jkchemical.com |
| Company Name: |
Energy Chemical |
| Tel: |
021-021-58432009 400-005-6266 |
| Fax: |
021-58436166 |
| WebSite: |
http://www.energy-chemical.com |
|