ChemicalBook >>Clofibrate>>Ethyl 2-(4-chlorophenoxy)-2-methylpropionate(637-07-0)

Ethyl 2-(4-chlorophenoxy)-2-methylpropionate(637-07-0)

Ethyl 2-(4-chlorophenoxy)-2-methylpropionate(637-07-0)
Product IdentificationBack to Contents
【Product Name】

Ethyl 2-(4-chlorophenoxy)-2-methylpropionate

2-(P-chlorophenoxy)-2-methylpropionic*acid ethyl
Ethyl 2-(4-chlorophenoxy)-2-methylpropionate
Ethyl clofibrate


【Molecular Weight】



【RTECS Class】

Tumorigen; Drug; Mutagen; Reproductive Effector; Human Data


【Beilstein Reference】

Physical and Chemical PropertiesBack to Contents

Oil. Faint characteristic odor.
【Solubility in water】

【Boiling Point】


1.138-1.144 g/cm3 (20 C)

Agent to lower plasma very-low-density-lipoprotein concn, agent to lower concn of plasma triglycerides.
【Refractive Index】

1.505 (19 C)
First Aid MeasuresBack to Contents

Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended.

If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.

Remove contaminated clothing. Wash exposed area with soap and water. If symptoms persist, seek medical attention. Launder clothing before reuse.

If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention.
Handling and StorageBack to Contents

Clofibrate liquid-filled capsules should be stored in well-closed, light-resistant containers, at a temperature less than 40C. Preferably at 15-30C; freezing of the liquid-filled capsules should be avoided.

All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Hazards IdentificationBack to Contents

Various rashes and alopecia have been reported.

Ausea, vomiting, constipation, dyspepsia, diarrhea, and flatulence occur transiently in approximately 10% of patients. Epigastric pain has been reported as a frequent side effect and cholelithiasis is increased.
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.

Use NIOSH/MSHA approved respirator appropriate for exposure of concern.
【Exposure Effects】

with therapeutic use - fatigue, weakness, drowsiness, dizziness, and headache have been reported during clofibrate therapy. Clofibrate and Fenofibrate are classified as FDA Pregnancy Category C.
Fire Fighting MeasuresBack to Contents
【Flash Point】

【Fire Fighting】

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces.
Stability and ReactivityBack to Contents

Sensitive to oxidation and light; easily hydrolyzed.

Strong oxidizing agents.
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