ChemicalBook >>Captopril>>Captopril(62571-86-2)

Captopril(62571-86-2)

Captopril(62571-86-2)
Product IdentificationBack to Contents
【Product Name】

Captopril
【Synonyms】

(2S)-1-(3-Mercapto-2-methylpropionyl)-L-proline
(2S)-1-[(2S)-2-Methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid
Acepress
Acepril
Alopresin
Capoten
【CAS】

62571-86-2
【Formula】

C9H15NO3S
【Molecular Weight】

217.29
【EINECS】

263-607-1
【RTECS】

UY0550000
【RTECS Class】

Drug; Reproductive Effector; Human Data
【Merck】

12,1817
【Beilstein/Gmelin】

477887
Physical and Chemical PropertiesBack to Contents
【Appearance】

White to off-white, crystalline powder. Slight acid-sulfhydryl odor.
【Solubility in water】

freely soluble
【Melting Point】

103 - 105
【pKa/pKb】

3.7 (pKa)
【Partition Coefficient】

.34
【Usage】

Antihypertensive drug.
First Aid MeasuresBack to Contents
【Ingestion】

Get medical aid. Wash mouth out with water.
【Inhalation】

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
【Skin】

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
【Eyes】

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Handling and StorageBack to Contents
【Storage】

Store in a cool, dry place. Store in a tightly closed container.
【Handling】

Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Hazards IdentificationBack to Contents
【Ingestion】

May cause irritation of the digestive tract.
【Inhalation】

Causes respiratory tract irritation. Inhalation may be fatal as a result of spasm, inflammation, edema of the larynx and bronchi, chemical pneumonitis and pulmonary edema. May be harmful if inhaled. May cause burning sensation, coughing, wheezing, laryngitis, shortness of breath, headache, nausea, and vomiting.
【Skin】

Causes skin irritation. May be harmful if absorbed through the skin. May cause sensitization by skin contact.
【Eyes】

Causes eye irritation.
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
【Respirators】

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Fire Fighting MeasuresBack to Contents
【Fire Fighting】

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing media: Use foam, dry chemical, or carbon dioxide.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

Vacuum or sweep up material and place into a suitable disposal container.
Stability and ReactivityBack to Contents
【Stability】

Stable under normal shipping and handling conditions.
【Incompatibilities】

Strong oxidizing agents, acids, acid chlorides, carbon dioxide, acid anhydrides.
【Decomposition】

Carbon monoxide, oxides of nitrogen, oxides of sulfur, carbon dioxide.
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