ChemicalBook >>Mizoribine>>5-Hydroxy-1-beta-D-ribofuranosyl-1H-imidazole-4-carboxamide(50924-49-7)

5-Hydroxy-1-beta-D-ribofuranosyl-1H-imidazole-4-carboxamide(50924-49-7)

5-Hydroxy-1-beta-D-ribofuranosyl-1H-imidazole-4-carboxamide(50924-49-7)
Product IdentificationBack to Contents
【Product Name】

5-Hydroxy-1-beta-D-ribofuranosyl-1H-imidazole-4-carboxamide
【Synonyms】

1H-Imidazole-4-carboxamide, 5-hydroxy-1-beta-D-ribofuranosyl-
4-Carbamoyl-1-beta-D-ribofuranosyl-imidazolium-5-olate
5-Hydroxy-1-beta-D-ribofuranosyl-1H-imidazole-4-carboxamide
Anhydro-4-carbamoyl-5-hydroxy-1-b-D-ribofuranosyl-imidazolium-hydroxide
Bredinin
HE-69
【CAS】

50924-49-7
【Formula】

C9H13N3O6
【Molecular Weight】

259.22000000000003
【RTECS】

NI3980000
【Merck】

12,6306
【Beilstein/Gmelin】

4151713
Physical and Chemical PropertiesBack to Contents
【Appearance】

A natural product, first isolated from the mold Eupenicillium brefeldianum.
【Solubility in water】

1.4 g/L (25 C)
【Density】

2.06 g/cm3 (20 C)
【pKa/pKb】

6.89 (pKa)
【Partition Coefficient】

-.17
【Usage】

An immunosuppresive drug.
First Aid MeasuresBack to Contents
【Ingestion】

If swallowed, wash out mouth with water provided person is conscious. Call a physician.
【Inhalation】

If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
【Skin】

In case of contact, immediately wash skin with soap and copious amounts of water. Remove contaminated clothing and shoes. Call a physician.
【Eyes】

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.
Handling and StorageBack to Contents
【Storage】

Store at 2 - 8 C.
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

Compatible chemical-resistant gloves. Chemical safety goggles. Protective clothing.
【Respirators】

Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Where risk assessment shows air-purifying respirators are appropriate use a full-face particle respirator type N99 (US) or type P2 (EN 143) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator.
【Exposure Effects】

May be harmful by inhalation, ingestion, or skin absorption. Reported to have immunosuppressive effect, causing decrease in number of leucocytes.
Fire Fighting MeasuresBack to Contents
【Fire Fighting】

Extinguish with water spray, carbon dioxide, dry chemical powder or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability and ReactivityBack to Contents
【Stability】

Stable at normal temperatures and pressures.
【Decomposition】

Oxides of carbon, oxides of nitrogen.
Hazards IdentificationBack to Contents
【Hazards】

Emits toxic fumes under fire conditions.
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