| Product Identification | Back to Contents | 【Product Name】
Astemizole | 【Synonyms】
1-((4-Fluorophenyl)methyl)-N-(1-(2-(4-methoxyphenyl)ethyl)-4-piperidinyl)-1H-benzimidazol-2-amine
1-(p-Fluorobenzyl)-2-((1-(b-methoxyphenethyl)-4-piperidyl)amino)benzimidazole
Astemison | 【CAS】
68844-77-9 | 【Formula】
C28H31FN4O | 【Molecular Weight】
458.58 | 【EINECS】
272-441-9 | 【RTECS】
DD8968000 | 【RTECS Class】
Drug; Reproductive Effector; Human Data | 【Merck】
12,891 | 【Beilstein/Gmelin】
4830190 |
| First Aid Measures | Back to Contents | 【Ingestion】
Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended. | 【Inhalation】
If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention. | 【Skin】
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. | 【Eyes】
If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention. |
| Handling and Storage | Back to Contents | 【Storage】
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage. | 【Handling】
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood. |
| Exposure Controls/Personal Protection | Back to Contents | 【Personal Protection】
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots. | 【Respirators】
Use NIOSH/MSHA approved respirator appropriate for exposure of concern. | 【Exposure Effects】
drowsiness may be noted. Generalized seizures were associated with an ingestion of 200 to 250 mg of astemizole in a previously healthy 15-year-old female. Astemizole is classified as FDA pregnancy category C. <br>It is not known whether or not astemizole is excreted in human breast milk. |
| Fire Fighting Measures | Back to Contents | 【Fire Fighting】
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire. |
| Accidental Release Measures | Back to Contents | 【Small spills/leaks】
Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces. |
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| Company Name: |
J & K SCIENTIFIC LTD. |
| Tel: |
010-82848833 400-666-7788 |
| Fax: |
86-10-82849933 |
| WebSite: |
http://www.jkchemical.com |
| Company Name: |
Spectrum Chemical Manufacturing Corp. |
| Tel: |
021-021-021-67601398-809-809-809 15221380277 |
| Fax: |
021-57711696 |
| WebSite: |
www.spectrumchemical.com/oa_html/index.jsp?minisite=10020&respid=22372&language=us |
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