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ChemicalBook >>Fluorocytosine>>2-Hydroxy-4-amino-5-fluoropyrimidine(2022-85-7)

2-Hydroxy-4-amino-5-fluoropyrimidine(2022-85-7)

2-Hydroxy-4-amino-5-fluoropyrimidine(2022-85-7)
Product IdentificationBack to Contents
【Product Name】

2-Hydroxy-4-amino-5-fluoropyrimidine
【Synonyms】

4-Amino-5-fluoro-2(1H)-pyrimidinone
4-Amino-5-fluoro-3H-pyrimidin-2-one
Alcobon
Ancobon
Ancotil
Flucytosine
【CAS】

2022-85-7
【Formula】

C4H4FN3O
【Molecular Weight】

129.09
【EINECS】

217-968-7
【RTECS】

HA6040000
【RTECS Class】

Drug; Mutagen; Human Data
【Merck】

13,4151
【Beilstein/Gmelin】

127285
【Beilstein Reference】

4-25-00-03688
Physical and Chemical PropertiesBack to Contents
【Solubility in water】

15 g/L
【Melting Point】

165
【Boiling Point】

298
【pKa/pKb】

3.26(at 25℃) (pKa)
【Partition Coefficient】

-1.07
【Usage】

Medication.
First Aid MeasuresBack to Contents
【Ingestion】

Get medical aid. Wash mouth out with water.
【Inhalation】

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
【Skin】

Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists.
【Eyes】

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. If irritation develops, get medical aid.
Handling and StorageBack to Contents
【Storage】

Store in a cool, dry place. Store in a tightly closed container.
【Handling】

Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Store protected from light.
Hazards IdentificationBack to Contents
【Inhalation】

May cause respiratory tract irritation.
【Skin】

May cause skin irritation.
【Eyes】

May cause eye irritation.
【Ingestion】

No hazard expected in normal industrial use.
【EC Risk Phrase】

R 40
【EC Safety Phrase】

S 22 36/37
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

Eyes: Wear chemical goggles. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear a chemical apron.
【Respirators】

A NIOSH/MSHA approved air purifying dust or mist respirator or European Standard EN 149.
【Exposure Effects】

Prolonged or repeated exposure may cause adverse reproductive effects.
Fire Fighting MeasuresBack to Contents
【Flash Point】

296
【Fire Fighting】

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

Vacuum or sweep up material and place into a suitable disposal container.
Stability and ReactivityBack to Contents
【Stability】

No data.
【Incompatibilities】

Strong oxidizing agents.
【Decomposition】

Nitrogen oxides, carbon monoxide, carbon dioxide, hydrogen fluoride.
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