| Product Identification | Back to Contents | 【Product Name】
Etoposide | 【Synonyms】
(-)-Etoposide, (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside
4'-Demethylepipodophyllotoxin 9-(4,6-O-ethylidene-beta-D-glucopyranoside)
9-((4,6-O-Ethylidene-beta-D-glucopyranosyl)oxy)-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-furo(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-6(5aH)-one
Lastet
Toposar
VePesid | 【CAS】
33419-42-0 | 【Formula】
C29H32O13 | 【Molecular Weight】
588.57000000000005 | 【EINECS】
251-509-1 | 【RTECS】
KC0190000 | 【RTECS Class】
Tumorigen; Drug; Mutagen; Reproductive Effector; Human Data | 【Merck】
12,3931 | 【Beilstein/Gmelin】
3659695 |
| First Aid Measures | Back to Contents | 【Ingestion】
Seek immediate medial attention. | 【Inhalation】
Seek immediate medial attention. | 【Skin】
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. | 【Eyes】
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility. |
| Handling and Storage | Back to Contents | 【Storage】
Store under refrigeration, in orginal container. | 【Handling】
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood. |
| Hazards Identification | Back to Contents | 【Inhalation】
Dyspnea, acute bronchospasm, apnea and cyanosis have been reported. Fatal pulmonary toxicity has been reported after oral use. | 【Skin】
Rash, urticaria and/or pruritus have been infrequently reported. Erythema and desquamation, alopecia, onycholysis, and stevens-johnson syndrome have occurred following therapeutic use of etoposide. | 【Eyes】
Conjunctivitis. | 【Ingestion】
Ausea, vomiting and diarrhea commonly occur. Paralytic ileus has been reported. |
| Exposure Controls/Personal Protection | Back to Contents | 【Personal Protection】
Surgical latex gloves -- which should be changed regularly. Safety goggles. | 【Respirators】
Use NIOSH/MSHA approved respirator appropriate for exposure of concern. | 【Exposure Effects】
Bone marrow supression. Cytotoxic agent. Anaphlactic-like reaction is possible. Possible carcinogen. |
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