ChemicalBook >>Tris(hydroxymethyl)aminomethane>>2-Amino-2-(hydroxymethyl)-1,3-propanediol(77-86-1)

2-Amino-2-(hydroxymethyl)-1,3-propanediol(77-86-1)

2-Amino-2-(hydroxymethyl)-1,3-propanediol(77-86-1)
Product IdentificationBack to Contents
【Product Name】

2-Amino-2-(hydroxymethyl)-1,3-propanediol
【Synonyms】

2-Amino-2-(hydroxymethyl)-1,3-propanediol
2-Amino-2-(hydroxymethyl)propane-1,3-diol
Aminotris(hydroxymethyl)methane
Tham
Tris(hydroxymethyl)methylamine
Tromethanmin
【CAS】

77-86-1
【Formula】

C4H11NO3
【Molecular Weight】

121.14
【EINECS】

201-064-4
【RTECS】

TY2900000
【RTECS Class】

Drug
【Merck】

12,9902
【Beilstein/Gmelin】

741883
【Beilstein Reference】

4-04-00-01903
【EC Class】

irritant
Physical and Chemical PropertiesBack to Contents
【Appearance】

Crystalline mass or white, crystalline powder, slight characteristic amine odor, hygroscopic.
【Solubility in water】

Very soluble
【Melting Point】

131
【Boiling Point】

357
【Vapor Pressure】

2E-6 (25 C)
【Density】

1.328 g/cm3
【pKa/pKb】

6.22 (pKb)
【Partition Coefficient】

-1.38
【Heat Of Vaporization】

69.7 kJ/mol
【Usage】

In synth of surface-active agents, vulcanization accelerators, pharmaceuticals: titrimetric standard, as emulsifying agent for cosmetic creams & lotions, mineral oil & paraffin wax emulsions, leather dressings, emulsifying agent for textile specialties, polishes, cleaning compd, so-called sol oils.
First Aid MeasuresBack to Contents
【Ingestion】

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
【Inhalation】

Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
【Skin】

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
【Eyes】

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Handling and StorageBack to Contents
【Storage】

Store in a cool, dry place. Keep away from acids. Keep containers tightly closed.
【Handling】

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation. Discard contaminated shoes.
Hazards IdentificationBack to Contents
【Inhalation】

May cause irritation of the respiratory tract with burning pain in the nose and throat, coughing, wheezing, shortness of breath and pulmonary edema.
【Skin】

May cause skin irritation.
【Eyes】

May cause eye irritation.
【Ingestion】

May cause severe gastrointestinal tract irritation with nausea, vomiting and possible burns.
【EC Risk Phrase】

R 36/37/38
【EC Safety Phrase】

S 26 36
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
【Respirators】

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
【Exposure Effects】

Prolonged or repeated skin contact may cause dermatitis.
【Poison Class】

-
Fire Fighting MeasuresBack to Contents
【Flash Point】

170
【Fire Fighting】

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

Clean up spills immediately, using the appropriate protective equipment. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal.
Stability and ReactivityBack to Contents
【Disposal Code】

28
【Incompatibilities】

Bases, oxidizing agents, acids, aldehydes, copper, brass, and aluminum.
【Stability】

Stable under normal temperatures and pressures.
【Decomposition】

Nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.
Transport InformationBack to Contents
【HS Code】

2922 19 80
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