| Product Identification | Back to Contents | 【Product Name】
2-Amino-2-(hydroxymethyl)-1,3-propanediol | 【Synonyms】
2-Amino-2-(hydroxymethyl)-1,3-propanediol
2-Amino-2-(hydroxymethyl)propane-1,3-diol
Aminotris(hydroxymethyl)methane
Tham
Tris(hydroxymethyl)methylamine
Tromethanmin | 【CAS】
77-86-1 | 【Formula】
C4H11NO3 | 【Molecular Weight】
121.14 | 【EINECS】
201-064-4 | 【RTECS】
TY2900000 | 【RTECS Class】
Drug | 【Merck】
12,9902 | 【Beilstein/Gmelin】
741883 | 【Beilstein Reference】
4-04-00-01903 | 【EC Class】
irritant |
| Physical and Chemical Properties | Back to Contents | 【Appearance】
Crystalline mass or white, crystalline powder, slight characteristic amine odor, hygroscopic. | 【Solubility in water】
Very soluble | 【Melting Point】
131 | 【Boiling Point】
357 | 【Vapor Pressure】
2E-6 (25 C) | 【Density】
1.328 g/cm3 | 【pKa/pKb】
6.22 (pKb) | 【Partition Coefficient】
-1.38 | 【Heat Of Vaporization】
69.7 kJ/mol | 【Usage】
In synth of surface-active agents, vulcanization accelerators, pharmaceuticals: titrimetric standard, as emulsifying agent for cosmetic creams & lotions, mineral oil & paraffin wax emulsions, leather dressings, emulsifying agent for textile specialties, polishes, cleaning compd, so-called sol oils. |
| First Aid Measures | Back to Contents | 【Ingestion】
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately. | 【Inhalation】
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. | 【Skin】
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. | 【Eyes】
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. |
| Handling and Storage | Back to Contents | 【Storage】
Store in a cool, dry place. Keep away from acids. Keep containers tightly closed. | 【Handling】
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation. Discard contaminated shoes. |
| Hazards Identification | Back to Contents | 【Inhalation】
May cause irritation of the respiratory tract with burning pain in the nose and throat, coughing, wheezing, shortness of breath and pulmonary edema. | 【Skin】
May cause skin irritation. | 【Eyes】
May cause eye irritation. | 【Ingestion】
May cause severe gastrointestinal tract irritation with nausea, vomiting and possible burns. | 【EC Risk Phrase】
R 36/37/38 | 【EC Safety Phrase】
S 26 36 |
| Exposure Controls/Personal Protection | Back to Contents | 【Personal Protection】
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. | 【Respirators】
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use. | 【Exposure Effects】
Prolonged or repeated skin contact may cause dermatitis. | 【Poison Class】
- |
| Fire Fighting Measures | Back to Contents | 【Flash Point】
170 | 【Fire Fighting】
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. |
| Accidental Release Measures | Back to Contents | 【Small spills/leaks】
Clean up spills immediately, using the appropriate protective equipment. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. |
| Stability and Reactivity | Back to Contents | 【Disposal Code】
28 | 【Incompatibilities】
Bases, oxidizing agents, acids, aldehydes, copper, brass, and aluminum. | 【Stability】
Stable under normal temperatures and pressures. | 【Decomposition】
Nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen. |
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