ChemicalBook >>Milrinone>>1,6-Dihydro-2-methyl-6-oxo-(3,4'-bipyridine)-5-carbonitrile(78415-72-2)

1,6-Dihydro-2-methyl-6-oxo-(3,4'-bipyridine)-5-carbonitrile(78415-72-2)

1,6-Dihydro-2-methyl-6-oxo-(3,4'-bipyridine)-5-carbonitrile(78415-72-2)
Product IdentificationBack to Contents
【Product Name】

1,6-Dihydro-2-methyl-6-oxo-(3,4'-bipyridine)-5-carbonitrile
【Synonyms】

1,6-Dihydro-2-methyl-6-oxo-(3,4'-bipyridine)-5-carbonitrile
6-Methyl-2-oxo-5-pyridin-4-yl-1H-pyridine-3-carbonitrile
WIN-47203
YM-018
【CAS】

78415-72-2
【Formula】

C12H9N3O
【Molecular Weight】

211.22
【EINECS】

278-903-6
【RTECS】

DW1762000
【RTECS Class】

Drug
【Merck】

12,6284
【Beilstein/Gmelin】

3546821
【Beilstein Reference】

6-25
Physical and Chemical PropertiesBack to Contents
【Appearance】

white solid
【Solubility in water】

Insoluble
【Melting Point】

313 - 316
【Boiling Point】

449
【Vapor Pressure】

3E-8 (25 C)
【Density】

1.344 g/cm3
【pKa/pKb】

8.83 (pKa)
【Partition Coefficient】

0
【Heat Of Vaporization】

70.7 kJ/mol
【Usage】

Potent cardiotonic, positive inotropic vasodilator.
First Aid MeasuresBack to Contents
【Ingestion】

If swallowed, wash out mouth with water provided person is conscious. Call a physician immediately.
【Inhalation】

If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
【Skin】

In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
【Eyes】

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.
Handling and StorageBack to Contents
【Storage】

Keep tightly closed. Store at 2-8 C
Hazards IdentificationBack to Contents
【Inhalation】

Toxic if inhaled. Material may be irritating to
【Skin】

May cause skin irritation. Toxic if absorbed through skin.
【Eyes】

May cause eye irritation.
【Ingestion】

Toxic if swallowed.
【Hazards】

Emits toxic fumes under fire conditions.
【UN (DOT)】

2811
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

Compatible chemical-resistant gloves. Chemical safety goggles.
【Respirators】

Government approved respirator.
【Exposure Effects】

Toxic by inhalation, in contact with skin and if swallowed. Possible sensitizer. Target organ(s): Heart. Smooth muscle.
Fire Fighting MeasuresBack to Contents
【Fire Fighting】

Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
【Fire Potential】

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability and ReactivityBack to Contents
【Stability】

Stable at normal temperatures and pressures.
【Incompatibilities】

Strong oxidizing agents.
【Decomposition】

Carbon monoxide, Carbon dioxide, Nitrogen oxides.
【Combustion Products】

Fire may produce irritating, corrosive and/or toxic gases.
Transport InformationBack to Contents
【UN Number】

2811
【Hazard Class】

6.1
【Packing Group】

III
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