| Product Identification | Back to Contents | 【Product Name】
Domperidone | 【Synonyms】
4-(5-Chloro-2-oxo-1-benzimidazolinyl)-1-[3-(2-oxobenzimidazolinyl)propyl]piperidine
5-Chloro-1-(1-(3-(2-oxo-1-benzimidazolinyl)propyl)-4-piperidyl)-2-benzimidazolinone
KW-5338
Motilium
Peridon | 【CAS】
57808-66-9 | 【Formula】
C22H24ClN5O2 | 【Molecular Weight】
425.92 | 【EINECS】
260-968-7 | 【RTECS】
DE2275900 | 【RTECS Class】
Drug; Reproductive Effector; Human Data | 【Merck】
12,3476 | 【Beilstein/Gmelin】
903774 | 【Beilstein Reference】
5-24-02-00402 |
| Physical and Chemical Properties | Back to Contents | 【Appearance】
White powder. | 【Solubility in water】
Insoluble | 【Melting Point】
236 - 239 | 【pKa/pKb】
4.80 (pKb) | 【Usage】
Peripheral dopamine receptor antagonist that does not cross the blood-brain barrier; anti-emetic. |
| First Aid Measures | Back to Contents | 【Ingestion】
If swallowed, wash out mouth with water provided person is conscious. Call a physician immediately. | 【Inhalation】
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen. | 【Skin】
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician. | 【Eyes】
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician. |
| Hazards Identification | Back to Contents | 【Inhalation】
May be harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract. | 【Skin】
May cause skin irritation. May be harmful if absorbed through the skin. | 【Eyes】
May cause eye irritation. | 【Ingestion】
May be harmful if swallowed. | 【Hazards】
Emits toxic fumes under fire conditions. |
| Exposure Controls/Personal Protection | Back to Contents | 【Personal Protection】
Compatible chemical-resistant gloves. | 【Respirators】
Government approved respirator. | 【Exposure Effects】
Harmful. Possible risk of harm to the unborn child. Possible risk of impaired fertility. Target organ(s): G.I. System. |
| Fire Fighting Measures | Back to Contents | 【Fire Fighting】
Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes. |
| Stability and Reactivity | Back to Contents | 【Stability】
Stable at normal temperatures and pressures. | 【Incompatibilities】
Strong oxidizing agents. | 【Decomposition】
Carbon monoxide, Carbon dioxide, Nitrogen oxides, Hydrogen chloride gas. |
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