Product Identification | Back to Contents | 【Product Name】
cis-1-Acetyl-4-(4-((2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazine | 【Synonyms】
1-[4-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]ethanone Fungoral Nizoral Nizral Piperazine, 1-acetyl-4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-, rel- R 41400 | 【CAS】
65277-42-1 | 【Formula】
C26H28Cl2N4O4 | 【Molecular Weight】
531.44000000000005 | 【EINECS】
265-667-4 | 【RTECS】
TK7912300 | 【RTECS Class】
Drug; Mutagen; Reproductive Effector; Human Data | 【Merck】
12,5313 | 【Beilstein/Gmelin】
4303081 |
First Aid Measures | Back to Contents | 【Ingestion】
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. | 【Inhalation】
Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask. | 【Skin】
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. | 【Eyes】
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. |
Handling and Storage | Back to Contents | 【Storage】
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. | 【Handling】
Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. |
Hazards Identification | Back to Contents | 【Inhalation】
May cause respiratory tract irritation. May cause thryoid effects. May cause liver damage. | 【Skin】
May cause skin irritation. | 【Eyes】
May cause eye irritation. | 【Ingestion】
Harmful if swallowed. May cause irritation of the digestive tract. May cause liver damage. May cause thyroid abnormalities. Human fatalities have been reported from acute poisoning. |
Exposure Controls/Personal Protection | Back to Contents | 【Personal Protection】
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. | 【Respirators】
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary. | 【Exposure Effects】
Chronic exposure may cause liver damage. Chronic exposure may cause thyroid damage: thyroid enlargement, decrease in metabolic rate, and hypothyroidism. Reproductive effects have been reported in humans. |
Fire Fighting Measures | Back to Contents | 【Fire Fighting】
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire use water spray, dry chemical, carbon dioxide, or appropriate foam. |
Accidental Release Measures | Back to Contents | 【Small spills/leaks】
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation. |
Stability and Reactivity | Back to Contents | 【Incompatibilities】
Oxidizing agents. | 【Stability】
Stable at room temperature in closed containers under normal storage and handling conditions. | 【Decomposition】
Hydrogen chloride, nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide. |
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