| Product Identification | Back to Contents | 【Product Name】
4-Nitrosophenol | 【Synonyms】
1,4-Benzoquinone monoxime
Nitrosophenol
para-Nitrosophenol
Quinone monoxime
Quinone oxime | 【CAS】
104-91-6 | 【Formula】
C6H5NO2 | 【Molecular Weight】
123.11 | 【EINECS】
203-251-6 | 【RTECS】
SM4725000 | 【RTECS Class】
Mutagen | 【Merck】
12,6740 | 【Beilstein/Gmelin】
1856695 | 【Beilstein Reference】
4-07-00-02073 | 【EC Index Number】
604-042-00-6 | 【EC Class】
Mutagenic Category 3; Harmful; Irritant; Dangerous for the Environment |
| Physical and Chemical Properties | Back to Contents | 【Appearance】
Yellow to brown powder. | 【Solubility in water】
8 g/L | 【Melting Point】
130 | 【Boiling Point】
266 | 【Vapor Pressure】
0.005 (25 C) | 【pKa/pKb】
6.48 (pKa) | 【Partition Coefficient】
1.43 | 【Heat Of Vaporization】
52.4 kJ/mol | 【Heat Of Combustion】
-3005 kJ/mol | 【Usage】
Manufacture of dyes. |
| First Aid Measures | Back to Contents | 【Ingestion】
Dilution - may enhance absorption of phenol, and should be avoided. Emesis: ipecac-induced vomiting is not recommended because of the potential for cns depression and seizures. Activated charcoal - may limit systemic toxicity if administered soon after ingestion, but may interfere with endoscopic evaluation of gastrointestinal burns. | 【Inhalation】
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. | 【Skin】
Get medical aid. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. | 【Eyes】
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility. |
| Handling and Storage | Back to Contents | 【Storage】
Keep away from sources of ignition. Store in a cool, dry place. Do not store in direct sunlight. Store in a tightly closed container. Flammables-area. | 【Handling】
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood. |
| Hazards Identification | Back to Contents | 【Inhalation】
Tachypnea is commonly reported; pulmonary edema and bronchospasm may also occur. Stridor has been reported from exposure to high concentrations of phenol. Respiratory arrest occurred 30 minutes post ingestion of 26.7 Grams of phenol in one case. | 【Skin】
Phenol is corrosive to the skin, but because of anesthetic qualities, it will numb rather than causing a burning pain on contact. Skin becomes red and swollen, then white and opaque. Deep burns result that may become gangrenous. | 【Eyes】
May cause eye irritation and possible damage. | 【Ingestion】
Phenol is extremely corrosive and may cause oral and esophageal burns and abdominal pain following ingestion. |
| Exposure Controls/Personal Protection | Back to Contents | 【Personal Protection】
Wear protective safety goggles or face shield as described in 29 CRF 1910.133 or European Standard EN166. Skin contact should be eliminated by wearing the appropriate chemical protective gloves annd clothing. | 【Respirators】
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary. | 【Exposure Effects】
Abnormally low blood pressure, reduced body temperature, rapid breathing, and rapid heart rate may develop with severe toxicity. Initial CNS excitation, including seizures, is commonly followed by CNS depression ranging from lethargy to coma and death. Fetotoxicity and skeletal abnormalities have been reported in animal experiments. | 【Poison Class】
1 |
| Fire Fighting Measures | Back to Contents | 【Flash Point】
115 | 【Autoignition】
390 | 【Fire Fighting】
Wear a self-contained breathing apparatus inpressure-demand, MSHA/NIOSH (approved or equivalent), and fullprotective gear. This material poses an explosion hazard when dry.Flammable solid. In case of fire use water spray, dry chemical, carbon dioxide, orchemical foam. |
| Accidental Release Measures | Back to Contents | 【Small spills/leaks】
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid generating dusty conditions. Remove all sources of ignition. Use a spark-proof tool. |
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