ChemicalBook >>Glipizide>>1-Cyclohexyl-3-[[p-[2-(5-methylpyrazinecarboxamido)ethyl]phenyl]sulfonyl]urea(29094-61-9)

1-Cyclohexyl-3-[[p-[2-(5-methylpyrazinecarboxamido)ethyl]phenyl]sulfonyl]urea(29094-61-9)

1-Cyclohexyl-3-[[p-[2-(5-methylpyrazinecarboxamido)ethyl]phenyl]sulfonyl]urea(29094-61-9)
Product IdentificationBack to Contents
【Product Name】

1-Cyclohexyl-3-[[p-[2-(5-methylpyrazinecarboxamido)ethyl]phenyl]sulfonyl]urea
【Synonyms】

1-Cyclohexyl-3-((p-(2-(5-methylpyrazinecarboxamido)ethyl)phenyl)sulfonyl)urea
Aldiab
Glipizide
Glydiazinamide
N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-5-methyl-pyrazine-2-carboxamide
Sucrazide
【CAS】

29094-61-9
【Formula】

C21H27N5O4S
【Molecular Weight】

445.53
【EINECS】

249-427-6
【RTECS】

YS7640000
【RTECS Class】

Drug; Human Data
【Merck】

12,4451
【Beilstein/Gmelin】

903495
Physical and Chemical PropertiesBack to Contents
【Appearance】

odorless white powder
【Solubility in water】

Insoluble
【Melting Point】

208-209
【pKa/pKb】

5.34 (pKa)
【Usage】

Antidiabetic agent. It sitimulates the release of insulin.
First Aid MeasuresBack to Contents
【Ingestion】

Get medical aid. Wash mouth out with water.
【Inhalation】

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
【Skin】

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
【Eyes】

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Handling and StorageBack to Contents
【Storage】

Store in a tightly closed container. Store in a dry area. Store at around 20 C.
【Handling】

Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Hazards IdentificationBack to Contents
【Ingestion】

May cause irritation of the digestive tract. May be harmful if swallowed. May cause salicylism with effects similar to skin
【Inhalation】

May cause respiratory tract irritation. May be harmful if inhaled. May cause salicylism with effects similar skin absorption.
【Skin】

May cause skin irritation. May be harmful if absorbed through the skin. Absorption through the skin may cause salicylism, characterized by deep and rapid breathing, nausea, vomiting, tinnitis, gastrointestinal irritation with possible ulcers and possible strokes.
【Eyes】

May cause eye irritation.
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
【Respirators】

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Fire Fighting MeasuresBack to Contents
【Fire Fighting】

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

Vacuum or sweep up material and place into a suitable disposal container.
Stability and ReactivityBack to Contents
【Stability】

No data.
【Incompatibilities】

Strong oxidizing agents.
【Decomposition】

Nitrogen oxides, carbon monoxide, carbon dioxide, hydrogen fluoride.
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